Isolation of triterpenic acid-rich extracts from Hedyotis corymbosa using ultrasound-assisted supercritical carbon dioxide extraction and determination of their fictitious solubilities

doi:10.1016/j.jiec.2017.01.003

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Title:	Isolation of triterpenic acid-rich extracts from Hedyotis corymbosa using ultrasound-assisted supercritical carbon dioxide extraction and determination of their fictitious solubilities
Authors:	Wei, Ming-Chi Hong, Show-Jen Yang, Yu-Chiao
Contributors:	Chia Nan Univ Pharm & Sci, Dept Appl Geoinformat Kaohsiung Med Univ, Dept & Grad Inst Pharmacol Kaohsiung Med Univ Hosp, Dept Med Res
Keywords:	Hedyotis corymbosa Oleanolic acid Ursolic acid Fictitious solubility Ultrasound-assisted supercritical CO2 extraction
Date:	2017-04-25
Issue Date:	2018-11-30 15:53:27 (UTC+8)
Publisher:	Elsevier Science Inc
Abstract:	The present study investigated a green ultrasound-assisted supercritical carbon dioxide (USC-CO2) process for extracting oleanolic acid (OA) and ursolic acid (UA) from Hedyotis corymbosa. Chrastil, Bartle and Kumar and Johnston models were used to correlate the experimental fictitious solubility data. The overall average absolute relative deviation (AARD (%)) in solid solubility ranged from 3.632% to 6.529%, which indicates good agreement between the experimental fictitious solubility data and the modeled results. Using the correlation results, the total heat of solution and the enthalpies of vaporization and solvation for OA and UA in the USC-CO2 extraction process were also estimated. (C) 2017 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.
Relation:	Journal of Industrial and Engineering Chemistry, v.48, pp.202-211
Appears in Collections:	[Dept. of Applied Geoinformatics] Periodical Articles

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