Epidemiology of cancer in end-stage renal disease dialysis patients: a national cohort study in Taiwan

doi:10.7150/jca.16550

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题名:	Epidemiology of cancer in end-stage renal disease dialysis patients: a national cohort study in Taiwan
作者:	Chien, Chih-Chiang Han, Ming-Ming Chiu, Yu-Hsien Wang, Jhi-Joung Chu, Chin-Chen Hung, Chien-Ya Sun, Yih-Min Yeh, Nai-Cheng Ho, Chung-Han Lin, Chih-Ching Kao, Hao-Yun Weng, Shih-Feng
贡献者:	Chi Mei Med Ctr, Dept Nephrol Chung Hwa Univ Med Technol, Dept Food Nutr Anhui Med Univ, Anhui Prov Hosp, Dept Anesthesiol, Hefei Kaohsiung Med Univ, Dept Healthcare Adm & Med Informat Chi Mei Med Ctr, Dept Med Res Chia Nan Univ Pharm & Sci, Dept Recreat & Hlth Care Management Chi Mei Med Ctr, Dept Anesthesiol Chung Hwa Univ Med Technol, Dept Occupat Safety & Hlth Chi Mei Med Ctr, Dept Endocrinol & Metab Taipei Vet Gen Hosp, Dept Nephrol
关键词:	Cancer end-stage renal disease incidence dialysis
日期:	2017
上传时间:	2018-11-30 15:52:47 (UTC+8)
出版者:	Ivyspring Int Publ
摘要:	The incidence and mortality of site-specific cancers in patients with end-stage renal disease (ESRD) on maintenance dialysis have been rarely studied for Asian populations. We tapped Taiwan`s National Health Insurance Research Database to identify and recruit patients starting maintenance dialysis between 1999 and 2004. They were followed from initiation of dialysis until death, discontinuation of dialysis, or the end of 2008. We calculated the survival rate and mortality risk of dialysis patients with cancer. Of 40,833 dialysis patients, 2352 (5.8%) had been newly diagnosed with cancer. Being older, being male, and having chronic liver disease were factors associated with a higher risk for new cancer in ESRD dialysis patients. In men, liver cancer (20.63%) was the most frequent, followed by cancers of the bladder (16.88%) and kidney (11.61%). In women, bladder cancer (25.57%) was the most frequent, followed by cancers of the kidney (16.31%) and breast (11.20%). The 5-year survival rates for kidney and bladder cancer were higher than for other cancers; the survival rates for lung, stomach, and liver cancer were lower. In conclusion, the distribution of site-specific cancer was different between men and women in patients with ESRD on dialysis. More attention should be paid to teaching dialysis patients how to avoid the well-known cancer risks and carcinogens and individualized regular cancer screenings.
關聯:	Journal of Cancer, v.8, n.1, pp.9-18
显示于类别:	[Dept. of Recreation and Health-Care Management] Periodical Articles

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