Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/31684
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    Title: Epidemiology of cancer in end-stage renal disease dialysis patients: a national cohort study in Taiwan
    Authors: Chien, Chih-Chiang
    Han, Ming-Ming
    Chiu, Yu-Hsien
    Wang, Jhi-Joung
    Chu, Chin-Chen
    Hung, Chien-Ya
    Sun, Yih-Min
    Yeh, Nai-Cheng
    Ho, Chung-Han
    Lin, Chih-Ching
    Kao, Hao-Yun
    Weng, Shih-Feng
    Contributors: Chi Mei Med Ctr, Dept Nephrol
    Chung Hwa Univ Med Technol, Dept Food Nutr
    Anhui Med Univ, Anhui Prov Hosp, Dept Anesthesiol, Hefei
    Kaohsiung Med Univ, Dept Healthcare Adm & Med Informat
    Chi Mei Med Ctr, Dept Med Res
    Chia Nan Univ Pharm & Sci, Dept Recreat & Hlth Care Management
    Chi Mei Med Ctr, Dept Anesthesiol
    Chung Hwa Univ Med Technol, Dept Occupat Safety & Hlth
    Chi Mei Med Ctr, Dept Endocrinol & Metab
    Taipei Vet Gen Hosp, Dept Nephrol
    Keywords: Cancer
    end-stage renal disease
    incidence
    dialysis
    Date: 2017
    Issue Date: 2018-11-30 15:52:47 (UTC+8)
    Publisher: Ivyspring Int Publ
    Abstract: The incidence and mortality of site-specific cancers in patients with end-stage renal disease (ESRD) on maintenance dialysis have been rarely studied for Asian populations. We tapped Taiwan`s National Health Insurance Research Database to identify and recruit patients starting maintenance dialysis between 1999 and 2004. They were followed from initiation of dialysis until death, discontinuation of dialysis, or the end of 2008. We calculated the survival rate and mortality risk of dialysis patients with cancer. Of 40,833 dialysis patients, 2352 (5.8%) had been newly diagnosed with cancer. Being older, being male, and having chronic liver disease were factors associated with a higher risk for new cancer in ESRD dialysis patients. In men, liver cancer (20.63%) was the most frequent, followed by cancers of the bladder (16.88%) and kidney (11.61%). In women, bladder cancer (25.57%) was the most frequent, followed by cancers of the kidney (16.31%) and breast (11.20%). The 5-year survival rates for kidney and bladder cancer were higher than for other cancers; the survival rates for lung, stomach, and liver cancer were lower. In conclusion, the distribution of site-specific cancer was different between men and women in patients with ESRD on dialysis. More attention should be paid to teaching dialysis patients how to avoid the well-known cancer risks and carcinogens and individualized regular cancer screenings.
    Relation: Journal of Cancer, v.8, n.1, pp.9-18
    Appears in Collections:[Dept. of Recreation and Health-Care Management] Periodical Articles

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