Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/31659
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    Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/31659


    Title: Mining Sequential Risk Patterns From Large-Scale Clinical Databases for Early Assessment of Chronic Diseases: A Case Study on Chronic Obstructive Pulmonary Disease
    Authors: Cheng, Yi-Ting
    Lin, Yu-Feng
    Chiang, Kuo-Hwa
    Tseng, Vincent S.
    Contributors: Natl Cheng Kung Univ, Inst Med Informat
    Natl Cheng Kung Univ, Dept Comp Sci
    Chi Mei Med Ctr, Div Chest Med, Dept Internal Med
    Chia Nan Univ Pharm & Sci
    Natl Chao Tung Univ, Dept Comp Sci
    Keywords: Data mining
    disease risk assessment
    early prediction
    electronic medical records
    sequential patterns
    Date: 2017-03
    Issue Date: 2018-11-30 15:51:53 (UTC+8)
    Publisher: Ieee-Inst Electrical Electronics Engineers Inc
    Abstract: Chronic diseases have been among the major concerns in medical fields since they may cause a heavy burden on healthcare resources and disturb the quality of life. In this paper, we propose a novel framework for early assessment on chronic diseases by mining sequential risk patterns with time interval information from diagnostic clinical records using sequential rules mining, and classification modeling techniques. With a complete workflow, the proposed framework consists of four phases namely data preprocessing, risk pattern mining, classification modeling, and post analysis. For empiricasl evaluation, we demonstrate the effectiveness of our proposed framework with a case study on early assessment of COPD. Through experimental evaluation on a large-scale nationwide clinical database in Taiwan, our approach can not only derive rich sequential risk patterns but also extract novel patterns with valuable insights for further medical investigation such as discovering novel markers and better treatments. To the best of our knowledge, this is the first work addressing the issue of mining sequential risk patterns with time-intervals as well as classification models for early assessment of chronic diseases.
    Relation: Ieee Journal of Biomedical and Health Informatics, v.21, n.2, pp.303-311
    Appears in Collections:[The Center For General Education] Periodical Articles

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