Chemical Constituents and Bioactivities from the twigs of Severinia buxifolia.

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Title:	Chemical Constituents and Bioactivities from the twigs of Severinia buxifolia.
Authors:	Peishian-Li (李佩銜) Yang-Chang Wu (吳永昌) Fang-Rong Chang (張芳榮) Yuan-Bin Cheng (鄭源斌) Liu Huang, Rosa (劉黃惠珠)
Contributors:	Graduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University School of Pharmacy, College of Pharmacy, China Medical University Research Center for Natural Products & Drug Development, Kaohsiung Medical University School of Nutrition, Chung Shan Medical University
Date:	2015-11-14
Issue Date:	2018-03-27 09:33:54 (UTC+8)
Abstract:	The family Rutaceae (Sapindales) is distributed over temperate and sub-tropical regions, and more than 160 genuses belong to it. Among them, 13 genuses have been found in Taiwan. Severinia buxifolia, a small evergreen tree, is native to southern China and Taiwan. In previous pharmacological studies, S. buxifolia was reported to have cytotoxic, anti-bacterial, and antiviral activities. As results of earlier natural product researches, triterpenes, coumarins, acridones, and various phenolic compounds were considered as the major constituents of S. buxifolia. In our current investigation, the methanol-soluble layer of the twigs of S. buxifolia showed promising anti-inflammatory activity. The purification of S. buxifolia led to one new peroxyterpenyl coumarin (1) along with seventeen known compounds (2–18). The structures of these compounds were determined by spectroscopic methods, especially 2D NMR analyses.
Relation:	2015台灣藥學年會暨學術研討會，起迄日：2015/11/14，地點：嘉南藥理大學
Appears in Collections:	[Pharmacy and Science] 2015 Annual symposium of the pharmaceutical society of Taiwan

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