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| 標題: | Clinical Significance of Community- and Healthcare-Acquired Carbapenem-Resistant Enterobacteriaceae Isolates |
| 作者: | Tang, Hung-Jen
Hsieh, Cheng-Fang
Chang, Ping-Chin
Chen, Jyh-Jou
Lin, Yu-Hsiu
Lai, Chih-Cheng
Chao, Chien-Ming
Chuang, Yin-Ching |
| 貢獻者: | Chi Mei Med Ctr, Dept Med
Chia Nan Univ Pharm & Sci, Dept Hlth & Nutr
Kaohsiung Med Univ, Kaohsiung Med Univ Hosp, Dept Internal Med, Div Geriatr & Gerontol
Kaohsiung Med Univ, Kaohsiung Med Univ Hosp, Dept Neurol
Chi Mei Med Ctr, Dept Internal Med
Chi Mei Med Ctr, Comm Infect Control
Chi Mei Med Ctr, Dept Intens Care Med
Min Hwei Coll Hlth Care Management, Dept Nursing
Chi Mei Med Ctr, Dept Med Res |
| 關鍵字: | nonsusceptible klebsiella-pneumoniae
escherichia-coli
united-states
risk-factors
epidemiology
taiwan
infections
multicenter
bacteremia
prevention |
| 日期: | 2016-03 |
| 上傳時間: | 2018-01-18 11:41:20 (UTC+8) |
| 出版者: | Public Library Science |
| 摘要: | This study was conducted to investigate the clinical significance, manifestations, microbiological characteristics and outcomes of carbapenem-resistant Enterobacteriaceae (wCRE) isolates, and compare the clinical features of community-and healthcare-acquired CRE isolates. A total of 78 patients were identified to have CRE. Klebsiella pneumoniae was the most common pathogens (n = 42, 53.8%), followed by Enterobacter cloacae (n = 24, 30.8%), and Escherichia coli (n = 11, 14.1%). Most of the patients acquired CRE from healthcare settings (n = 55, 70.5%), and other cases got CRE from community settings (n = 23, 29.5%). Nine cases (11.5%) were classified as CRE colonization. Among the remaining 69 cases of CRE infections, pneumonia (n = 28, 40.6%) was the most common type of infections, followed by urinary tract infection (n = 24, 34.8%), and intra-abdominal infection (n = 16, 23.2%). The patients acquired CRE from community settings were more likely to be elderly, female, and had more urinary tract infections than from healthcare settings. In contrast, the patients acquired CRE from healthcare settings had more intra-abdominal infections, intra-abdominal surgery, and presence of indwelling device than from community settings. In conclusion, community-acquired CRE are not rare, and their associated clinical presentations are different from healthcare-acquired CRE. |
| 關聯: | Plos One, v.11 n.3, e0151897 |
| 顯示於類別: | [保健營養系(所) ] 期刊論文
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