Increased risk of sudden sensorineural hearing loss in patients with depressive disorders: population-based cohort study

doi:10.1017/S0022215115002960

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Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/31010

Title:	Increased risk of sudden sensorineural hearing loss in patients with depressive disorders: population-based cohort study
Authors:	Lin, C-S Lin, Y-S Liu, C-F Weng, S-F Lin, C. Lin, B-S
Contributors:	Chi Mei Med Ctr, Dept Otolaryngol Chi Mei Med Ctr, Dept Med Res Chung Hwa Univ Med Technol, Dept Nursing Chia Nan Univ Pharm & Sci, Dept Hosp & Hlth Care Adm Univ Calif Berkeley, Dept Mol & Cell Biol Natl Chiao Tung Univ, Inst Imaging & Biomed Photon
Keywords:	Hearing Loss Sudden Depressive Disorder
Date:	2016-01
Issue Date:	2018-01-18 11:39:46 (UTC+8)
Publisher:	Cambridge Univ Press
Abstract:	Objectives: To evaluate the incidence rates and risk of sudden sensorineural hearing loss among patients with depressive disorders. Method: Data for 27 547 patients with newly diagnosed depressive disorders and 27 547 subjects without depressive disorders between 2001 and 2008 were yielded from the Taiwan National Health Insurance Research Database. Sudden sensorineural hearing loss incidence at the end of 2011 was determined. Cumulative incidence and adjusted hazard ratio were computed. Results: Sudden sensorineural hearing loss incidence was 1.45 times higher in the depressive disorders group compared to the non-depressive disorders group (p = 0.0041), with an adjusted hazard ratio of 1.460. A significant increased risk of developing sudden sensorineural hearing loss was noted in patients with diabetes mellitus, chronic kidney disease and hyperlipidaemia (p < 0.05). Conclusion: The results suggest an increased risk of developing sudden sensorineural hearing loss in patients with depressive disorders. Co-morbidities such as diabetes mellitus, chronic kidney disease and hyperlipidaemia significantly aggravated the risk. Depressive disorders might be considered a risk factor for sudden sensorineural hearing loss. It remains to be seen whether control of depressive disorders can decrease the incidence of sudden sensorineural hearing loss in patients with depressive disorders.
Relation:	Journal of Laryngology and Otology, v.130 n.1, pp.42-49
Appears in Collections:	[Dept. of Hospital and Health (including master's program)] Periodical Articles

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