Development of a Green Alternative Procedure for the Simultaneous Separation and Quantification of Clove Oil and Its Major Bioactive Constituents

doi:10.1021/acssuschemeng.6b01263

CNU IR > College of Sustainable Environment and Recreation > Dept. of Applied Geoinformatics > Periodical Articles > Item 310902800/30976

Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/30976

Title:	Development of a Green Alternative Procedure for the Simultaneous Separation and Quantification of Clove Oil and Its Major Bioactive Constituents
Authors:	Wei, Ming-Chi Lin, Pei-Hui Hong, Show-Jen Chen, Jin-Ming Yang, Yu-Chiao
Contributors:	Chia Nan Univ Pharm & Sci, Dept Appl Geoinformat Ohio State Univ, Wexner Med Ctr, Davis Heart & Lung Res Inst, Dept Surg Kaohsiung Med Univ, Dept & Grad Inst Pharmacol
Keywords:	Clove oil Eugenyl acetate Eugenol beta-Catyophyllene alpha-Humulene Ultrasound -assisted supercritical CO2 extraction Solubility quantitation
Date:	2016-12
Issue Date:	2018-01-18 11:39:04 (UTC+8)
Publisher:	Amer Chemical Soc
Abstract:	Clove buds are a good source of oil, which can be used as a food flavor and traditional Chinese medicine. To isolate clove oil and its major bioactive constituents, a green alternative procedure employing ultrasound-assisted supercritical carbon dioxide (USC-CO2) extraction combined with gas chromatography/mass spectrometry was developed, and its performance was compared to those of conventional processes. The green USC-CO2 process saves time, solvent, energy, and raw materials without chemical waste while achieving superior yields of clove oil and major bioactive constituents. The solubility of clove oil and fictitious solubility of eugenol in SC-CO2 have been predicted for the first time at various temperatures (32-50 degrees C) and pressures (9.0-28.5 MPa). Furthermore, solubility data correlated well with three density based models (Chrastil, Kumar-Johnston, and Bartle), and the overall average absolute relative deviations (AARD%) were 0.22, 0.92, and 4.91%, respectively. Using correlation results, we approximated the enthalpies for clove oil. The total heat of solution, heat of solvation, and heat of vaporization for clove oil were 9.83, 19.03, and -9.69 kJ/mol, respectively.
Relation:	Acs Sustainable Chemistry & Engineering, v.4 n.12, pp.6491-6499
Appears in Collections:	[Dept. of Applied Geoinformatics] Periodical Articles

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