Risk of Rhegmatogenous Retinal Detachment with Central Serous Chorioretinopathy

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Title:	Risk of Rhegmatogenous Retinal Detachment with Central Serous Chorioretinopathy
Authors:	Chang, Yuh-Shin Chang, Chun Weng, Shih-Feng Wang, Jhi-Joung Jan, Ren-Long
Contributors:	Chi Mei Med Ctr, Dept Ophthalmol Chang Jung Christian Univ, Grad Inst Med Sci, Coll Hlth Sci Univ Taipei, Dept Educ Chi Mei Med Ctr, Med Res Chia Nan Univ Pharm & Sci, Dept Hosp & Hlth Care Adm Chi Mei Med Ctr, Anesthesiol Chi Mei Med Ctr, Dept Pediat Natl Cheng Kung Univ, Grad Inst Clin Med
Keywords:	central serous chorioretinopathy National Health Insurance Research Database population-based study rhegmatogenous retinal detachment
Date:	2016-08
Issue Date:	2018-01-18 11:38:51 (UTC+8)
Publisher:	Lippincott Williams & Wilkins
Abstract:	Purpose: To investigate the risk of rhegmatogenous retinal detachment (RRD) after central serous chorioretinopathy (CSCR). Methods: The study included 2,830 patients with CSCR and 16,980 control patients matched using a propensity score for age, sex, and comorbidities including status after cataract operation, blunt trauma, myopia, diabetes mellitus, hypertension, and hyperlipidemia from January 2001 through December 2010 from the Taiwan Longitudinal Health Insurance Database 2000. Information of each patient was collected until December 2011. Cox proportional hazard regression analysis was used to obtain the adjusted hazard ratio for RRD. The RRD-free survival rate was calculated using Kaplan-Meier analysis. Results: Thirty-five patients with CSCR (1.24%) and 27 controls (0.16%) had RRD (P < 0.0001) during follow-up, resulting in a significantly higher risk of RRD in the patients with CSCR (incidence rate ratio = 7.83, 95% confidence interval = 4.74-12.93). After adjustment for potential confounders, the adjusted hazard ratio for developing RRD was increased 7.85 times in the cohort of total sample (adjusted hazard ratio = 7.85, 95% confidence interval = 4.75-12.97). Conclusion: It was found that CSCR increased the risk of RRD even after adjustment for age, sex, and comorbidities including status after cataract operation, blunt trauma, myopia, diabetes mellitus, hypertension, and hyperlipidemia.
Relation:	Retina-The Journal of Retinal and Vitreous Diseases, v.36 n.8, pp.1446-1453
Appears in Collections:	[Dept. of Hospital and Health (including master's program)] Periodical Articles

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