Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/30677
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    Title: 白鶴靈芝草降尿酸之功效探討
    Authors: 吳海平
    Contributors: 嘉南藥理大學保健營養系(含碩士班)
    蕭慧美
    Keywords: 高尿酸血症
    尿酸
    白鶴靈芝
    hypoxanthine
    Date: 2014
    Issue Date: 2017-12-13 11:32:35 (UTC+8)
    Abstract: 白鶴靈芝是台灣民間的常見草藥。本實驗想測試白鶴靈芝是否有降尿酸的效果且可做為預防痛風的保健產品。本實驗使用ICR 雄性小鼠,並分為六組,分別為控制組(C)、高尿酸血症組(HX,hypoxanthine 腹腔注射500mg/kg BW)、治療組(HX+AL,Allopurinol 10 mg/kg BW)、高劑量組(HX+RH,白鶴靈芝水萃物200 mg/kgBW)、中劑量組(HX+RM,白鶴靈芝水萃物100 mg/kg BW)、低劑量組(HX+RL,白鶴靈芝水萃物50 mg/kg BW)。實驗期八天,第一階段於前四天先管餵白鶴靈芝水萃物,最後一天才注射hypoxanthine (HX) 後一小時採血,第二階段則連續四天皆於管餵水萃物後即注射HX,過一小時後再採血犧牲。結果顯示HX 組之血清尿酸值顯著高於控制組,表示高尿酸血症動物模型成功建立。但樣品組血清尿酸值皆皆與HX 組無顯著差異,初步推斷短期餵食白鶴靈芝對於動物體內尿酸濃度的無顯著降低效用。
    Relation: 計畫編號:103-2815-C-041-016-B
    計畫年度:103;執行起迄:2014-07-01~2015-02-28
    Appears in Collections:[Dept. of Health and Nutrition (including master's program)] Bachelor's Monographs

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