Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/30222
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    標題: 以不同抽取法提取傳統中草藥之高價值生化活性成分
    Comparison of different extraction techniques for the extraction of high valuable bioactive compounds from traditional medicinal plant
    作者: 魏明治
    貢獻者: 應用空間資訊系
    關鍵字: Perilla frutescens
    essential oil
    perillaldehyde
    green extraction technique
    ultrasound-assisted supercritical CO2 extraction.
    日期: 2016
    上傳時間: 2017-02-16 16:10:29 (UTC+8)
    摘要: Introduction:
    Perilla frutescens leaves is valuable as a medicinal plant as well as a natural medicine and functional food. Perilla leaves are an important source of essential oils and had antidepressive, anxiolytic, chemopreventive and strong antitumor-promoting activities.
    Methods:
    Four different isolation techniques, specifically ultrasound-assisted supercritical carbon dioxide (USC-CO2) extraction, heat-reflux extraction (HRE), conventional supercritical carbon dioxide (SC-CO2) extraction and hydrodistillation (HD) were employed to obtain essential oils from purple-leafed of Perilla frutescens. The essential oils were further analyzed using gas chromatography (GC) with flame ionization detection and gas chromatography with mass spectrometry (GC-MS). Results: The maximum yield of oil was extracted via USC-CO2 extraction (1.62%, weight of the extracted oil/weight of feeding material) while utilizing less severe operating parameters, such as temperature (49 °C), pressure (28 MPa), organic solvent (0 mL) and the time consumed (105 min) by the process. The results revealed that the dominant component was perillaldehyde (> 40%) in total average content.
    Discussion:
    To evaluate the feasibility of supercritical separation processes and for establishing optimum operation conditions, a second-order kinetic model and a mass transfer model based on Fick’s law were applied to appraise the kinetics and thermodynamics aspects of perilla oil extraction employing the USC-CO2 systems. Additionally, the thermodynamic properties of essential oil in the supercritical fluid system were estimated following the theory developed by the second-order kinetic model and a mass transfer models.
    關聯: 計畫編號：CN10527；計畫年度：105
    显示于类别:[應用空間資訊系(所)] 校內計畫

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