台灣蕘花 (Wikstroemia taiwanensis, Thymelaeaceae)生長於台灣南部低海拔區，在台灣民間常用於清熱解毒、消炎等，而關於台灣蕘花的研究，只有在2012年由Chen Li-Yin等在其莖部發現數個構造新奇的bisflavonoids 如wikstaiwanones A, B, C, sikokianins B, C, isochamaejasmin等，其中sikokianins B, C有抗結核作用。因此，相信在台灣蕘花的根部應該還能找到一些更奇特的物質，故進行根的成份研究。目前在台灣蕘花的根部中分離出三個化合物，經光譜分析後，確定其中一個化合物為sikokianin B (1)，另外Compound 2與3目前進行構造解析中。在未來的研究上，期待能找夠找到更多具有藥理活性的化合物。 Wikstroemia taiwanensis (Thymelaeaceae) grows in south of Taiwan, about the research of W. taiwanensis, several bisflavonoids, such as wikstaiwanones A, B, C, sikokianins B, C and isochamaejasmin isolated from the stems was reported by Li-Yin Chen, Doctor of Philosophy in 2012, and sikokianins B, C showed antitubercular activity. We believe more exotic substances from the roots of W. taiwanensis will be isolated. Three compounds were isolated from the roots of W. taiwanensis. One was determined to be sikokianin B (1) by spectral analysis. The others of structural analysis is ongoing. Hope to find more bioactive compounds in the future.
