Diffusion-Weighted Magnetic Resonance Imaging and Apparent Diffusion Coefficient Mapping for Diagnosing Infectious Spondylodiscitis: A Preliminary Study

doi:10.1111/jon.12145

Chia Nan University of Pharmacy & Science Institutional Repository > 環境永續暨休閒學院 > 職業安全衛生系(含防災所) > 期刊論文 > Item 310902800/29744

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標題:	Diffusion-Weighted Magnetic Resonance Imaging and Apparent Diffusion Coefficient Mapping for Diagnosing Infectious Spondylodiscitis: A Preliminary Study
作者:	Chen, Tai-Yuan Wu, Te-Chang Tsui, Yu-Kun Chen, Hou-Hsun Lin, Chien-Jen Lee, Huey-Jen Wu, Tai-Ching
貢獻者:	嘉南藥理大學
關鍵字:	Apparent diffusion coefficient Degenerative disc disease Diffusion-weighted imaging Infectious spondylodiscitis Magnetic resonance imaging
日期:	2015-05
上傳時間:	2016-04-19 19:06:38 (UTC+8)
出版者:	Wiley-Blackwell
摘要:	BACKGROUND AND PURPOSEThough diffusion-weighted (DW) magnetic resonance imaging (MRI) is useful for diagnosing many pathologies, its use in infectious spondylodiscitis is unclear. We aimed to evaluate the use of DW MRI and apparent diffusion coefficient (ADC) mapping for the diagnosis of infectious spondylodiscitis. METHODSIn this retrospective study, 17 patients with confirmed infectious spondylodiscitis were matched by age and level of infected disc with 17 patients with degenerative disc disease (DDD) and 17 healthy controls. All patients received conventional MRI and diffusion-weighted imaging (DWI) in the same imaging session. ADC values of the 3 groups of patients were compared. RESULTSThe mean age of each group was 67.4 11.6 years. The mean ADCs of the normal control, DDD, and infectious spondylodiscitis groups were 1.76 +/- 0.19 x 10(-3), 1.12 +/- 0.22 x 10(-3), and 1.27 +/- 0.38 x 10(-3) mm(2)/second, respectively. The ADCs of the DDD and infectious spondylodiscitis groups were both significantly lower than that of the normal control group (both, P < 0.001). CONCLUSIONThese data suggest that DWI/ADC MRI may be useful in the early diagnosis of infectious spondylodiscitis.
關聯:	Journal of Neuroimaging, v.25 n.3, pp.482-487
顯示於類別:	[職業安全衛生系(含防災所)] 期刊論文

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