Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/29711
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    题名: Epidemiological profile of Dupuytren's disease in Taiwan (Ethnic Chinese): a nationwide population-based study
    作者: Yeh, Chin-Choon
    Huang, Kuo-Feng
    Ho, Chung-Han
    Chen, Kuan-Ting
    Liu, Cheng
    Wang, Jhi-Joung
    Chu, Chin-Chen
    贡献者: 休閒保健管理系
    关键词: Dupuytren’s disease
    Epidemiology
    Ethnic
    Chinese
    日期: 2015-02
    上传时间: 2016-04-19 19:05:29 (UTC+8)
    出版者: Biomed Central Ltd
    摘要: Background: The epidemiologic profile of ethnic Chinese patients with Dupuytren's disease is unknown. We therefore investigated the epidemiology of Dupuytren's disease using Taiwan's National Health Insurance Research Database.
    Methods: Patients who filed claims for treatment for Dupuytren's disease between January 2000 and December 2011 were identified in the database. Age-and gender-specific incidences were estimated by dividing the incidence number by population data.
    Results: We identified 1,078 patients with Dupuytren's disease (681 men, 397 women; male/female ratio: 1: 1.72). The annual incidence rate ranged from 0.39-0.63/105 for men and 0.14-0.44/10(5) for women. A trend analysis revealed a rising trend in the annual incidence from 2001 to 2011 (p = 0.0199). The prevalence rate increased steadily from 0.46/10(5) in 2000 to 4.52/10(5) in 2011 (p = 0.0186). The mean age at onset was significantly higher in men than in women (60.7 +/- 18.4 vs. 53.7 +/- 15.5 years). Peak age at onset for men was 70-79 (28.1%) and for women was 50-59 (33.5%). Men > 60 years old had higher incidence rates than did women (incidence rate ratios: 2.0, 4.5, and 6.6 for those 60-69, 70-79, and = 80, respectively). Hypertension (29.6%), diabetes mellitus (21.9%), hyperlipidemia (14.8%), ischemic heart disease (10.5%), and chronic obstructive pulmonary disease (8.0%) were the most common comorbidities.
    Conclusions: The incidence and prevalence of Dupuytren's disease and the male/female ratio were significantly lower in ethnic Chinese than in Western ethnic groups. Moreover, the age at onset was significantly lower in ethnic Chinese women. However, the incidences of three comorbidities (hypertension, diabetes mellitus, and hyperlipidemia) were similar to those in other ethnicities.
    關聯: Bmc Musculoskeletal Disorders, v.16 n.20
    显示于类别:[Dept. of Recreation and Health-Care Management] Periodical Articles

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