Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/29673
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    標題: Chronic Indwelling Urinary Catheter Increase the Risk of Bladder Cancer, Even in Patients Without Spinal Cord Injury
    作者: Ho, Chung-Han
    Sung, Kuan-Chin
    Lim, Sher-Wei
    Liao, Chien-Hwa
    Liang, Fu-Wen
    Wang, Jhi-Joung
    Wu, Chia-Chun
    貢獻者: 醫務管理系
    藥學系
    關鍵字: benignprostatichyperplasia
    rat
    inflammation
    population
    carcinogenesis
    enhancement
    association
    tumors
    日期: 2015-10
    上傳時間: 2016-04-19 19:04:08 (UTC+8)
    出版者: Lippincott Williams & Wilkins
    摘要: Chronic indwelling urinary catheters (CIDCs) are known as a risk factor for bladder cancer in patients with spinal cord injury (SCI). This study examined the potential risk of bladder cancer from CIDCs in patients without SCI.The National Health Insurance Research Database in Taiwan was used to identify SCI patients (N=1816). This group was compared against a control CIDC cohort without SCI (N=1816) and a reference cohort with normal individuals without SCI and a record of CIDC (N=7264). Comparisons were made based on age and gender matching over a maximum of 11 follow-up years. The incidence risk and hazard ratio (HR) of bladder cancer were estimated in all 3 groups.During the follow-up period, the bladder cancer incidence rates were 68.90 and 102.53 per 100,000 person-years in the SCI and CIDC-non-SCI groups, respectively. These values were both higher than that of the reference cohort (12.00 per 100,000 person-years). Patients who had history of SCI (HR: 6.51; 95% CI, 2.56-16.52) or CIDC without SCI (HR: 9.11; 95% CI, 3.9-21.29) had a higher risk of bladder cancer compared with the reference cohort.Patients with CIDCs may have an increased risk of bladder cancer development, especially in older aged and male patients compared with general population.
    關聯: Medicine, v.94 n.43, Article ID e1736
    显示于类别:[藥學系(所)] 期刊論文
    [醫務管理系(所)] 期刊論文

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