Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/29600
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    標題: The risk of acute coronary syndrome after retinal artery occlusion: a population-based cohort study
    作者: Chang, Yuh-Shin
    Chu, Chin-Chen
    Weng, Shih-Feng
    Chang, Chun
    Wang, Jhi-Joung
    Jan, Ren-Long
    貢獻者: 休閒保健管理系
    醫務管理系
    關鍵字: Myocardial-infarction
    Heart-disease
    Obstruction
    Events
    Atherosclerosis
    Disorders
    Serotonin
    Emboli
    日期: 2015-02
    上傳時間: 2016-04-19 19:01:37 (UTC+8)
    出版者: Bmj Publishing Group
    摘要: Aim To investigate the risk of acute coronary syndrome (ACS) following retinal artery occlusion (RAO).Methods The study cohort included all patients diagnosed with RAO between January 1999 and December 2008 (n=688) in the Taiwan Longitudinal Health Insurance Database 2000. The control group included randomly selected patients (n=4128) from the same database that were matched to the study group, using a propensity score, for age, gender, and comorbid diabetes mellitus, hypertension, hyperlipidaemia, chronic renal disease and atrial fibrillation status. The ACS-free survival rate was calculated using Kaplan-Meier analysis. Cox proportional hazard regression analysis was used to obtain the adjusted HR for ACS after adjustment for potential confounding factors. The incidence and risk of ACS were compared between the RAO and control groups.Results Thirty-seven patients in the RAO group (5.38%) and 138 controls (3.34%) had ACS (p=0.0063) during the follow-up period, resulting in a significantly higher risk of ACS in the RAO group (HR=1.67, 95% CI 1.16 to 2.40). After adjustment for potential confounders, the HR for developing ACS in the RAO group was 1.72 (95% CI 1.20 to 2.47) times higher than that of controls. When stratified by RAO type, the adjusted HR for ACS was 3.57 (95% CI 2.09 to 6.10) for the central RAO subgroup.Conclusions We found that RAO increased the risk for ACS. We recommend thorough follow-up cardiovascular examinations and medical prevention for ACS in patients following RAO.
    關聯: British Journal of Ophthalmology, v.99 n.2, pp.227-231
    顯示於類別:[醫務管理系(所)] 期刊論文
    [休閒保健管理系(所)] 期刊論文

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