Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/29305
English  |  正體中文  |  简体中文  |  Items with full text/Total items : 18076/20274 (89%)
Visitors : 5266597      Online Users : 1202
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
    •  Adv. Search
    Home ‧ Login ‧ Upload ‧ Help ‧ About ‧ Administer Goto mobile version


    Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/29305


    Title: Protective Effects of Selected Phenolic Compounds on Oxidative Stress
    Authors: Tarnrat Pattanawong
    Contributors: 保健營養系
    陳師瑩
    杜平惪
    Keywords: Tarnrat Pattanawong
    antioxidant
    t-BHP
    oxidative stress
    HepG2 cells
    Date: 2014
    Issue Date: 2015-10-26 20:31:31 (UTC+8)
    Abstract: The aim of this study was to evaluate the effect of selected phenolic compounds on oxidative stress. The phenolic compounds in the range of 50-500 ?g/ml showed no cytoxicity in the growth of HepG2 cells except Chrysin, Flavones, Galangin, and Baicalein.Flavonols, such as Quercetin, Morin, Myricetin, Rutin, Fisetin, and Kaemferol, and some phenolic acids such as Caffeic acid, and Chlorogenic, show greater protection on in the growth of HepG2 cells induced by 0.1 mM t-BHP than flavones, such as Chrysin, Baicalein, Apigenin, Nobilelin, and Tangeretin. For ROS generation, Quercetin, Morin, Myricetin, Rutin, Fisetin, Kaemferol, and Caffeic acid showed significant protection in these models. For mitochondrial membrane potential tests, Quercetin, Morin, Myricetin, Fisetin, Kaemferol, Caffeic acid and Chlorogenic acid showed significant protection mitochondrial membrane potential in these models. For the acellular tests, Quercetin, Morin, Myricetin, Rutin, Fisetin, Kaemferol, Caffeic acid, and Chlorogenic acid increased SOD activity and the inhibition of DPPH and NO. In cellular and acellular model systems, Quercetin, Morin, Myricetin, Rutin, Fisetin, Kaemferol, Caffeic, and Chlorogenic demonstrated significantly inhibitory effect on oxidative stress due to their remarkable antioxidant activity.
    Relation: 網際網路公開：2019-12-31，學年度：102，48頁
    Appears in Collections:[Dept. of Health and Nutrition (including master's program)] Dissertations and Theses

    Files in This Item:

    File Description SizeFormat
    index.html0KbHTML1467View/Open


    All items in CNU IR are protected by copyright, with all rights reserved.

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback