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https://ir.cnu.edu.tw/handle/310902800/28737
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標題: | Wound Dehiscence as a Cataract Surgery-Associated Postoperative Complication in Patients Previously Treated With Alpha-1 Blocker Tamsulosin-A Population-Based Study in Taiwan |
作者: | Hsiao, Ching-Hsing Ho, Chung-Han Liao, Chien-Hwa Wang, Hsien-Yi Wang, Jhi-Joung Wu, Chia-Chun |
貢獻者: | 老人服務事業管理系 藥學系 休閒保健管理系 |
關鍵字: | FLOPPY-IRIS-SYNDROME ANTAGONISTS SUBTYPES |
日期: | 2014-12 |
上傳時間: | 2015-05-06 21:27:00 (UTC+8) |
出版者: | Elsevier Science Inc |
摘要: | PURPOSE: To compare the cataract surgery related complications between patients with and without tamsulosin treatment. DESIGN: A nationwide retrospective case-control study. METHODS: Patients who had undergone cataract surgery were identified using the International Classification of Disease, Ninth Revision, Clinical Modification from a nationally representative dataset of 1 million people selected from the Taiwan National Health Insurance Research Database in 2000. Patients preoperatively treated with alpha(1)-blockers before cataract surgery were the treated group, and age-, sex-, and year of surgery matched patients not preoperatively treated with alpha(1)-blockers were the control group. Patients treated with tamsulosin underwent subgroup analysis. A conditional logistic regression model was used to estimate surgery-related complications and interesting variables. The main outcome measures are cataract surgery related complications. RESULTS: A total of 4474 treated patients and 4474 controls were analyzed. The percentage of cataract surgery related complications was 8.61% in the treated group and 8% in the control group (not significantly different). However, wound dehiscence was 3.81 times higher (95% confidence interval: 1.24-11.67, P = .0194) in the tamsulosin-treated group. CONCLUSIONS: Patients treated with tamsulosin have a higher risk of wound dehiscence after cataract surgery. Carefully taking a history of tamsulosin use before cataract surgery is advised so that some strategies can be used to prevent complications and additional costs. (C) 2014 by Elsevier Inc. All rights reserved. |
關聯: | American Journal of Ophthalmology, v.158 n.6, pp.1215-1220 |
顯示於類別: | [休閒保健管理系(所)] 期刊論文 [藥學系(所)] 期刊論文 [高齡福祉養生管理系] 期刊論文
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