Revised iScore to Predict Outcomes after Acute Ischemic Stroke

doi:10.1016/j.jstrokecerebrovasdis.2014.01.010

Chia Nan University of Pharmacy & Science Institutional Repository > 藥理學院 > 化妝品應用與管理系(所) > 期刊論文 > Item 310902800/28676

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標題:	Revised iScore to Predict Outcomes after Acute Ischemic Stroke
作者:	Sung, Sheng-Feng Chen, Yu-Wei Hung, Ling-Chien Lin, Huey-Juan
貢獻者:	化粧品應用與管理系
關鍵字:	Acute ischemic stroke prediction risk score outcome prognosis
日期:	2014-07
上傳時間:	2015-05-06 21:24:47 (UTC+8)
出版者:	Elsevier Science Bv
摘要:	The iScore is a validated tool to predict mortality and functional outcome after acute ischemic stroke. It incorporates stroke subtype according to the Trial of Org 10172 in Acute Stroke Treatment (TOAST) classification as one of its factors. However, the TOAST stroke subtype may not be easily determined without extensive investigations. We aimed to test if the stroke subtype can be substituted by the Oxfordshire Community Stroke Project (OCSP) classification. We applied the iScore and the revised iScore, in which the TOAST subtype was replaced by the OCSP classification, to patients admitted to a single hospital for acute ischemic stroke. Outcome measures included poor functional status (modified Rankin scale score, 3-6) at discharge and 3 months. The performance between the iScore and the revised iScore was assessed by determining the discrimination and calibration of the scores. We studied 3196 patients at the acute stage, and among them 2349 patients were available for the 3-month assessment. The discrimination of the revised iScore was comparable with the iScore for poor outcome at discharge (area under the receiver operating characteristic curve,.767 versus .775; P=.06) and at 3-month (.801 versus .810; P=.06). The correlation between the observed and the expected outcomes was high for both the iScore (Pearson correlation coefficient, .993 at discharge and .995 at 3 months; both P < .0001) and the revised iScore (.985 and .993, respectively; both P < .0001). The revised iScore reliably predicts clinical outcomes at discharge and 3 months for patients with acute ischemic stroke.
關聯:	Journal of Stroke & Cerebrovascular Diseases, v.23 n.6, pp.1634-1639
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