Clinical Manifestations of Bacteremia Caused by Aeromonas Species in Southern Taiwan

doi:10.1371/journal.pone.0091642

CNU IR > Pharmacy and Science > Dept. of Health and Nutrition (including master's program) > Periodical Articles > Item 310902800/28528

Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/28528

Title:	Clinical Manifestations of Bacteremia Caused by Aeromonas Species in Southern Taiwan
Authors:	Tang, Hung-Jen Lai, Chih-Cheng Lin, Hsin-Lan Chao, Chien-Ming
Contributors:	保健營養系
Keywords:	INFECTION SOBRIA HYDROPHILA EPISODES PATIENT COMPLEX CAVIAE
Date:	2014-03
Issue Date:	2015-05-06 21:19:31 (UTC+8)
Publisher:	Public Library Science
Abstract:	Aim: This study is conducted to investigate the clinical characteristics of patients with bacteremia caused by Aeromonas species. Materials and Methods: Patients with bacteremia caused by Aeromonas species during the period 2009 to 2013 were identified from a computerized database of a regional hospital in southern Taiwan. The medical records of these patients were retrospectively reviewed. Results: A total of 91 patients with bacteremia due to Aeromonas species were identified. In addition to 16 (17.6%) primary bacteremia, the most common source of secondary infection is peritonitis (n = 27, 29.7%), followed by biliary tract infection (n = 18, 19.8%), and SSTI (n = 12, 13.2%), pneumonia (n = 9, 9.9%), catheter-related bloodstream infection (n = 5, 5.5%), and genitourinary tract infection (n = 4, 4.4%). A. hydrophila (n = 35, 38.5%) was the most common pathogen, followed by A. veronii biovar sobria (n = 31, 34.1%), A. caviae (n = 14, 15.4%), and A. veronii biovar veronii (n = 9, 9.9%). Forty-three (47.3%) patients were classified as healthcare-associated infections (HCAI) causes by Aeromonas species, and patients with HCAI were more likely to have cancer, and receive immunosuppressant than patients with community-acquired bacteremia. The overall outcomes, including rate of ICU admission, acute respiratory failure, and mortality were 33.3%, 28.6%, and 23.1%, respectively. Multivariate analysis showed that the in-hospital day mortality was significantly associated only with underlying cancer (P <.001), and initial shock (P <.001). Conclusions: Aeromonas species should be considered one of the causative pathogens of healthcare-associated bacteremia, especially in immunocompromised patients. In addition, it can be associated with high fatality. Cancer and initial shock were the poor prognostic factors.
Relation:	Plos One, v.9 n.3, e91642
Appears in Collections:	[Dept. of Health and Nutrition (including master's program)] Periodical Articles

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