Studies on the Effect of the Purified Snake Toxins on ATPase Activities of the Skeletal Muscle Membrane

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Title:	Studies on the Effect of the Purified Snake Toxins on ATPase Activities of the Skeletal Muscle Membrane
Authors:	Yang Meei-Shieu
Contributors:	私立嘉南藥學專科學校
Date:	1976
Issue Date:	2014-12-25 15:03:11 (UTC+8)
Abstract:	Coora cardiotoxin (CTX) has been shown to induce contracture of the skeletal muscle possibly by releasing the membrance Ca++. 1) β-bungarotoxin (β-BuTX) fo bungarus multicinctus venom blocks neuromuscular (N-M) transmission presynatically at the motor nerne ending. 2,3) It has been postulated that the mechanism of β-BuTX on N-M transmission may involve a direct or an indirect inhibition of Ca++ uptake by mitochondria inside the nerve terminals. 4) Since Ca++-activated ATPase is required for the Ca++ uptake of the membrane, 5) it would be of int erest to see if these two toxins exerts effects on the membrane Ca++ by the inhibition of this enzyme activity.
Relation:	嘉南學報, n.2 pp.91-99
Appears in Collections:	[Chna Nan Annual Bulletin] Vol.2 (1976)

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