移動相中添加β-環糊精在逆相液相層析上分離一些單取代酚類位置異構物

CNU IR > Chna Nan Annual Bulletin > Vol.39 (2013) > Item 310902800/28073

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Title:	移動相中添加β-環糊精在逆相液相層析上分離一些單取代酚類位置異構物 Separation of Some Isomeric Monosubstituted Phenols by RPLC Using β-cyclodextrin as Mobile Phase Additives
Authors:	李冠儀張書文賴鈺森林振興
Contributors:	輔英科技大學應用化學及材料科學系
Keywords:	逆相液相層析 β-環糊精硝基酚甲酚乙酚萘酚 Reversed Phase Liquid Chromatography β-Cyclodextrin Nitrophenol Cresol Ethylphenol naphthol
Date:	2013-12
Issue Date:	2014-10-02 16:05:57 (UTC+8)
Abstract:	本研究在移動相中添加5 mM β-環糊精於甲醇與水的混合溶液，利用RP-C18 靜相管柱分離一些單取代酚類位置異構物，並探討移動相中甲醇含量的影響。由層析結果顯示甲醇與水比例，會顯著影響單取代酚?位置?構物的分?效果。添加 5 mM β-環糊精於適當比例的甲醇與水的混合溶液當移動相，利用RP-C18 靜相管柱可以有效分離硝基酚、甲酚、乙酚以及萘酚位置異構物，且硝基酚與乙酚可以達到基線分離。 The retention behavior of some isomeric mono-substituted phenols was investigated by high-performance liquid chromatography on a RP-C18 stationary phase using β-cyclodextrin as mobile phase additives. Effects of methanol content of mobile phase were examined. Effective separations of some isomeric mono-substituted phenols were achieved on a RP-C18 stationary phase using β-cyclodextrin as mobile phase additives. Moreover, baseline separations of isomeric nitrophenol and ethylphenol were achieved.
Relation:	嘉南學報(科技類), n.39, pp.56-62
Appears in Collections:	[Chna Nan Annual Bulletin] Vol.39 (2013)

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