The Inhibitory Effects of Aqueous Extract from Guava Twigs, Psidium guajava L., on Mutation and Oxidative Damage

doi:10.1155/2013/561905

Chia Nan University of Pharmacy & Science Institutional Repository > 智慧生活學院 > 生活保健科技系 > 期刊論文 > Item 310902800/27943

請使用永久網址來引用或連結此文件: https://ir.cnu.edu.tw/handle/310902800/27943

標題:	The Inhibitory Effects of Aqueous Extract from Guava Twigs, Psidium guajava L., on Mutation and Oxidative Damage
作者:	Kang, Zhi-Chyang Yen, Ming-Tsung Chiu, Chih-Kwang Wu, Horng-Cherng Huang, Shu-Ling Tai, Shan-Pao Wang, Bor-Sen
貢獻者:	生活應用與保健系保健營養系食品科技系
關鍵字:	Mutagenicity Diseases Rats
日期:	2013
上傳時間:	2014-05-26 10:50:00 (UTC+8)
出版者:	Hindawi Publishing Corporation
摘要:	This study examines the inhibitory effects of the aqueous extract from guava twigs (GTE), Psidium guajava L., on mutation and oxidative damage. The results show that GTE inhibits the mutagenicity of 4-nitroquinoline-N-oxide (4-NQO), a direct mutagen, and 2-aminoanthracene (2-AA), an indirect mutagen, toward Salmonella typhimurium TA 98 and TA 100. In addition, GTE shows radical scavenging, reducing activities, tyrosinase inhibition, and liposome protection effects. Meanwhile, GTE in the range of 0.1-0.4 mg/mL protects liver cells from tert-butyl-hydroperoxide-(t-BHP-) induced cytotoxicity. Furthermore, the cytotoxicity inhibition of GTE in the t-BHP-treated cells was demonstrated in a dose-dependent manner. High-performance liquid chromatography analysis suggests that the major phenolic constituents in GTE are gallic acid, ferulic acid, and myricetin. These active phenolic components may contribute to the biological protective effects of GTE in different models. The data suggest that GTE exhibiting biological activities can be applied to antimutation, antityrosinase, and antioxidative damage.
關聯:	Journal of Chemistry, v.2013 n.561905
顯示於類別:	[生活保健科技系] 期刊論文 [保健營養系(所) ] 期刊論文 [ 食品科技系 ] 期刊論文

文件中的檔案:

檔案	描述	大小	格式	瀏覽次數
310902800_27943.pdf		1801Kb	Adobe PDF	806	檢視/開啟
index.html		0Kb	HTML	1835	檢視/開啟

在CNU IR中所有的資料項目都受到原著作權保護.

TAIR相關文章

資料載入中.....