Epidemiology and mortality among dialysis patients with acute coronary syndrome: Taiwan National Cohort Study

doi:10.1016/j.ijcard.2012.06.108

CNU IR > College of Smart Living > Dept. of Life and Health Science > Periodical Articles > Item 310902800/27842

Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/27842

Title:	Epidemiology and mortality among dialysis patients with acute coronary syndrome: Taiwan National Cohort Study
Authors:	Chou, Ming-Ting Wang, Jhi-Joung Sun, Yih-Min Sheu, Ming-Jen Chu, Chin-Chen Weng, Shih-Feng Chio, Chung-Ching Kan, Wei-Chih Chien, Chih-Chiang
Contributors:	生活應用與保健系醫藥化學系
Keywords:	Acute Coronary Syndrome Dialysis Mortality
Date:	2013-09
Issue Date:	2014-05-26 10:45:53 (UTC+8)
Publisher:	Elsevier Ireland Ltd
Abstract:	Background: Patients with end-stage renal disease (ESRD) on dialysis have poor outcomes after acute coronary syndrome (ACS). Epidemiological data for Asian patients are scarce.Methods: This longitudinal cohort study investigated the incidence, risk factors, and outcomes of ACS in 19,974 ESRD incident dialysis patients in the Taiwan National Health Insurance research Database between January 1999 and December 2001. The follow-up period was from the start of dialysis to the date of death, end of dialysis, or December 31, 2008.Results: ACS was diagnosed in 1785 patients during follow-up (1.78/100 person-years): 832 (46.6%) had acute myocardial infarction (AMI), 681 (38.2%) underwent cardiac catheterization, 398 (22.3%) underwent percutaneous transluminal coronary angioplasty (PTCA), and 50 (2.8%) underwent coronary artery bypass grafting. Male (HR 1.35, 95% CI: 1.23-1.49) and elderly (HR 3.289, 95% CI: 2.71-4.00) patients had a high rate of ACS. Patients with baseline comorbidities (diabetes mellitus, hypertension, congestive heart failure, coronary artery disease, dysrhythmia, and other cardiac and chronic obstructive lung diseases) had a higher incidence of ACS than did those without. Overall in-hospital mortality was 9.7%. The cumulative 6-month post-hospitalization survival rate was 79.3%; the 1-year rate was 72.3%. Being elderly (>= 65 years old), and having DM or AMI were associated with an increased risk for mortality; PTCA was associated with a decreased risk (HR 0.77, 95% CI: 0.66-0.91).Conclusion: ESRD dialysis patients had a high incidence of ACS and mortality. Being male, elderly and having baseline comorbidities were independent risk factors for ACS. Coronary intervention is the possible benefits for dialysis patients. (C) 2012 Elsevier Ireland Ltd. All rights reserved.
Relation:	International Journal of Cardiology, v.167 n.6 pp.2719-2723
Appears in Collections:	[Dept. of Life and Health Science] Periodical Articles [Dept. of Food & Drug Industry and Inspective Technology] Periodical Articles

Files in This Item:

File	Description	Size	Format
index.html		0Kb	HTML	1954	View/Open

Loading...