Comparison of protective effects of three varieties of sugarcane leaves on oxidative stress in Clone 9 cells

doi:10.1016/j.jff.2013.01.037

Chia Nan University of Pharmacy & Science Institutional Repository > 藥理學院 > 食品科技系 > 期刊論文 > Item 310902800/27808

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標題:	Comparison of protective effects of three varieties of sugarcane leaves on oxidative stress in Clone 9 cells
作者:	Lee, Chia-Pu Chen, Zong-Tsi Yu, Pei-Ying Yen, Wen-Ye Lin, Kuo-Min Duh, Pin-Der
貢獻者:	食品科技系醫藥化學系
關鍵字:	Clone 9 Cells Protective Effect Oxidative Stress Sugarcane Leaves
日期:	2013-04
上傳時間:	2014-05-26 10:44:31 (UTC+8)
出版者:	Elsevier Science Bv
摘要:	The protective effects of water extracts of sugarcane (Saccharum officinarum L.) leaves among three varieties, including 28NG256, wild type, and ROC10, on t-BHP-induced oxidative stress in Clone 9 cells were systematically compared. Among these three varieties, 28NG256 showed the highest protective effect against 0.2 mM t-BHP-induced oxidative stress in Clone 9 cells. In addition, 28NG256 displayed higher inhibitory effects on ROS generation than wild type and ROC10. Moreover, 28NG256 showed higher positive regulated GSH levels and antioxidant enzymes as well as higher protective potential against cell death by inhibiting caspase-3 activity and mitochondrial membrane depolarization. Chlorogenic and caffeic acids present in 28NG256 decreased significantly the generation of ROS, which may partly be responsible for the effect of Clone 9 cell growth. Thus, 28NG256, among the three varieties studied, showed the most protective effects against t-BHP-induced oxidative stress in Clone 9 cells. (C) 2013 Elsevier Ltd. All rights reserved.
關聯:	Journal of Functional Foods, v.5 n.2 pp.878-887
显示于类别:	[ 食品科技系 ] 期刊論文 [食藥產業暨檢測科技系(含五專)] 期刊論文

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