Biliary tract infections caused by Aeromonas species

doi:10.1007/s10096-012-1736-1

CNU IR > Pharmacy and Science > Dept. of Health and Nutrition (including master's program) > Periodical Articles > Item 310902800/27783

Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/27783

Title:	Biliary tract infections caused by Aeromonas species
Authors:	Chao, C. M. Lai, C. C. Tang, H. J. Ko, W. C. Hsueh, P. -R.
Contributors:	保健營養系
Keywords:	Acute Suppurative Cholangitis Genus Aeromonas Liver-Cirrhosis Bacteremia Patient Presentations Peritonitis Episodes Disease Spp.
Date:	2013-02
Issue Date:	2014-05-26 10:43:30 (UTC+8)
Publisher:	Springer
Abstract:	This study investigated the clinical and microbiological characteristics of patients with Aeromonas infections of the biliary tract. Patients with bile cultures positive for Aeromonas species during the period July 2004 to December 2011 were identified from a computerized database of a hospital in Taiwan. Patients with Aeromonas infections of the biliary tract were further identified. During the study period, a total of 1,142 isolates of Aeromonas species were obtained from 750 patients. Of those patients, 91 (12.1 %) had Aeromonas infections of the biliary tract. The annual incidence (episodes per 10,000 patient-days) of biliary tract infections caused by all Aeromonas species was 0.31 in 2007, 0.12 in 2010, and 0.27 in 2011. A. hydrophila was the most common species isolated (n = 41, 45.1 %), followed by A. caviae (n = 30, 33.0 %), A. veronii biovar sobria (n = 15, 16.5 %), and A. veronii biovar veronii (n = 5, 5.5 %). The majority of patients (n = 77, 84.6 %) had polymicrobial infections. Hepatobiliary stones (n = 50, 54.9 %) and hepatobiliary cancer (n = 38, 41.8 %) were the most common underlying diseases, followed by diabetes mellitus (n = 29, 31.9 %) and liver cirrhosis (n = 7, 7.7 %). The in-hospital mortality rate was 8.8 %. Infection-related mortality was associated with underlying immunocompromised condition (p = 0.044) and use of mechanical ventilation (p = 0.004), but was not associated with inappropriate antibiotic usage or concomitant bacteremia (n = 8, 8.8 %). In conclusion, biliary tract infections caused by Aeromonas species are not uncommon and can develop in both immunocompromised and immunocompetent patients; however, patients with underlying hepatobiliary diseases are particularly susceptible to these infections.
Relation:	European Journal of Clinical Microbiology & Infectious Diseases, v.32 n.2 pp.245-251
Appears in Collections:	[Dept. of Health and Nutrition (including master's program)] Periodical Articles

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