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https://ir.cnu.edu.tw/handle/310902800/27704
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| 標題: | Antioxidant and Anti-Inflammatory Properties of Longan (Dimocarpus longan Lour.) Pericarp |
| 作者: | Huang, Guan-Jhong
Wang, Bor-Sen
Lin, Wei-Chao
Huang, Shyh-Shyun
Lee, Chao-Ying
Yen, Ming-Tsung
Huang, Ming-Hsing |
| 貢獻者: | 化妝品應用與管理系 |
| 關鍵字: | Oxidative Stress
Free-Radicals
Fruit
Rat
Inflammation
Glutathione
Mechanisms
Chemistry
Extract
Enzymes |
| 日期: | 2012 |
| 上傳時間: | 2014-03-21 16:18:13 (UTC+8) |
| 出版者: | Hindawi Publishing Corporation |
| 摘要: | This study examined the antioxidant and anti-inflammatory activities of the water extract of longan pericarp (WLP). The results showed that WLP exhibited radical scavenging, reducing activity and liposome protection activity. In addition, WLP also inhibited lipopolysaccharide (LPS)-induced nitric oxide (NO) production in macrophages. Further, administration of WLP, in the range of 100-400 mg/kg, showed a concentration-dependent inhibition on paw edema development following carrageenan (Carr) treatment in mice. The anti-inflammatory effects of WLP may be related to NO and tumor necrosis factor (TNF-alpha) suppression and associated with the increase in the activities of antioxidant enzymes, including catalase, superoxide dismutase, and glutathione peroxidase. Overall, the results showed that WLP might serve as a natural antioxidant and inflammatory inhibitor. |
| 關聯: | Evidence-Based Complementary And Alternative Medicine, 709483,10 pages |
| 显示于类别: | [化妝品應用與管理系(所)] 期刊論文
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