Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/27702
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    Title: Antioxidant and Antityrosinase Activity of Flemingia macrophylla and Glycine tomentella Roots
    Authors: Wang, Bor-Sen
    Juang, Lih-Jeng
    Yang, Jeng-Jer
    Chen, Li-Ying
    Tai, Huo-Mu
    Huang, Ming-Hsing
    Contributors: 食品科技系
    化妝品應用與管理系
    Keywords: Antiinflammatory Activities
    Tyrosinase
    Constituents
    Isoflavones
    Flavonoids
    Chemistry
    Oxidation
    Genistein
    Daidzein
    Cells
    Date: 2012
    Issue Date: 2014-03-21 16:18:10 (UTC+8)
    Publisher: Hindawi Publishing Corporation
    Abstract: The antioxidant and antityrosinase activities of the water extract of Flemingia macrophylla root (WEFM) were investigated. The results showed that WEFM exhibited radical scavenging and reducing activities, as well as ferrous ion chelating property. In addition, WEFM also protected phospholipids against oxidation, indicating that WEFM could protect biomolecules from oxidative damage. Meanwhile, in the range of 50-100 mu g/mL, the tyrosinase inhibitory activity of WEFM increased with an increase in sample concentration and was superior to that of the water extract of Glycine tomentella root (WEGT). A high performance liquid chromatography analysis was used to determine the phenolic components, revealing that daidzin, daidzein, genistin, and genistein were present in WEFM and WEGT. Acting as an antioxidant and a tyrosinase inhibitor, these bioactive constituents could contribute to the protective effects of WEFM. Overall, the results showed that WEFM might serve as a natural antioxidant and tyrosinase inhibitor.
    Relation: Evidence-Based Complementary And Alternative Medicine, 431081,7 pages
    Appears in Collections:[Dept. of Food Science & Technology] Periodical Articles
    [Dept. of Cosmetic Science and institute of cosmetic science] Periodical Articles

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