In vitro susceptibilities of non-Enterobacteriaceae isolates from patients with intra-abdominal infections in the Asia-Pacific region from 2003 to 2010: results from the Study for Monitoring Antimicrobial Resistance Trends (SMART)

doi:10.1016/S0924-8579(12)70004-3

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標題:	In vitro susceptibilities of non-Enterobacteriaceae isolates from patients with intra-abdominal infections in the Asia-Pacific region from 2003 to 2010: results from the Study for Monitoring Antimicrobial Resistance Trends (SMART)
作者:	Liu, Yuag-Meng Chen, Yao-Shen Toh, Han-Siong Huang, Chi-Chang Lee, Yu-Lin Ho, Cheng-Mao Lu, Po-Liang Ko, Wen-Chien Chen, Yen-Hsu Wang, Jen-Hsien Tang, Hung-Jen Yu, Kwok-Woon Liu, Yung-Ching Chuang, Yin-Ching Xu, Yingchun Ni, Yuxing Liu, Chun-Eng Hsueh, Po-Ren
貢獻者:	保健營養系
關鍵字:	Intra-Abdominal Infections Antimicrobial Susceptibility Non-Enterobacteriaceae Gram-Negative Bacilli Pseudomonas Aeruginosa Acinetobacter Baumannii Smart
日期:	2012-06
上傳時間:	2014-03-21 16:15:55 (UTC+8)
出版者:	Elsevier Science Bv
摘要:	The Study for Monitoring Antimicrobial Resistance Trends (SMART) is an international surveillance study designed to monitor resistance trends among aerobic and facultative Gram-negative bacilli (GNB) isolated from intra-abdominal infections. During 2003-2010, a total of 20710 GNB isolates were collected at medical centers in China, Hong Kong, Korea, New Zealand, and Taiwan. The susceptibility profiles of 2252 isolates of non-Enterobacteriaceae GNB were determined. At least 10 isolates of a given organism were required for that organism to be included in the analysis. Pseudomonas aeruginosa was the leading organism (49.2% of non-Enterobacteriaceae GNB), followed by Acinetobacter baumannii (21.5%), Aeromonas spp. (11.6%), and Stenotrophomonas maltophilia (9.1%). All the other species/genera made up less than 2%. The rates of susceptibility of the four major organisms were examined for two different time periods and according to whether the isolates had been obtained <48 h after hospitalization or >= 48 h after hospital admission. P. aeruginosa, Aeromonas spp., and S. maltophilia showed sustained levels of susceptibility to several antimicrobial agents in the two time periods, whereas A. baumannii exhibited very high rates of resistance to most antimicrobial agents including imipenem. Nosocomial P. aeruginosa and A. baumannii were more resistant than community-acquired pathogens, although this was not the case for Aeromonas spp. and S. maltophilia. Worldwide and regional surveillance is necessary to guide empirical antimicrobial therapy for infections due to non-Enterobacteriaceae GNB. (C) 2012 Elsevier B. V. and the International Society of Chemotherapy. All rights reserved.
關聯:	International Journal of Antimicrobial Agents v.40 S1 pp.S11-S17
顯示於類別:	[保健營養系(所) ] 期刊論文

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