Lipid accumulation product: a simple and accurate index for predicting metabolic syndrome in Taiwanese people aged 50 and over

doi:10.1186/1471-2261-12-78

CNU IR > Pharmacy and Science > Dept. of Biotechnology (including master's program) > Periodical Articles > Item 310902800/27564

Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/27564

Title:	Lipid accumulation product: a simple and accurate index for predicting metabolic syndrome in Taiwanese people aged 50 and over
Authors:	Chiang, Jui-Kun Koo, Malcolm
Contributors:	生物科技系
Keywords:	Adiposity Chinese Metabolic Syndrome Prediction
Date:	2012-09-24
Issue Date:	2014-03-21 16:13:38 (UTC+8)
Publisher:	Biomed Central Ltd
Abstract:	Background: Lipid accumulation product (LAP) has been advocated as a simple clinical indicator of metabolic syndrome (MS). However, no studies have evaluated the accuracy of LAP in predicting MS in Taiwanese adults. The aim of our investigation was to use LAP to predict MS in Taiwanese adults.Methods: Taiwanese adults aged 50 years and over (n = 513) were recruited from a physical examination center at a regional hospital in southern Taiwan. MS was defined according to the MS criteria for Taiwanese people. LAP was calculated as (waist circumference [cm] -65) x (triglyceride concentration [mM]) for men, and (waist circumference [cm] -58) x (triglyceride concentration [mM]) for women. Simple logistic regression and receiver-operating characteristic (ROC) analyses were conducted.Results: The prevalence of MS was 19.5 and 21.5% for males and females, respectively. LAP showed the highest prediction accuracy among adiposity measures with an area under the ROC curve (AUC) of 0.901. This was significantly higher than the adiposity measure of waist-to-height ratio (AUC = 0.813).Conclusions: LAP was a simple and accurate predictor of MS in Taiwanese people aged 50 years and over. LAP had significantly higher predictability than other adiposity measures tested.
Relation:	Bmc Cardiovascular Disorders, 12(78)
Appears in Collections:	[Dept. of Biotechnology (including master's program)] Periodical Articles

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