An efficient total synthesis of Benzocamphorin H and its anti-inflammatory activity

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Title:	An efficient total synthesis of Benzocamphorin H and its anti-inflammatory activity
Authors:	Liao, Yu-Ren Kuo, Ping-Chung Huang, Shiow-Chyn Liang, Jun-Weil Wu, Tian-Shung
Contributors:	藥學系
Keywords:	Antrodia Camphorata Benzocamphorin H Anti-Inflammatory
Date:	2012-11-14
Issue Date:	2014-03-21 16:12:29 (UTC+8)
Publisher:	Pergamon-Elsevier Science Ltd
Abstract:	A naturally occurring enynyl-benzenoid, Benzocamphorin H (1), from the edible fungus Taiwanofungus camphoratus (Antrodia camphorata) was characterized by the comprehensive spectral analysis. It displayed potent anti-inflammatory bioactivity and would be valuable for further biological studies. The present study is the first total synthesis of Benzocamphorin H and the developed strategy described a more efficient procedure that allowed large-scale production of Benzocamphorin H for the further research of biological activity both in vitro and in vivo. (C) 2012 Elsevier Ltd. All rights reserved.
Relation:	Tetrahedron Letters, 53(46), 6202-6204
Appears in Collections:	[Dept. of Pharmacy] Periodical Articles

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