Inhibitory effects of water extract from longan twigs on mutation and nitric oxide production

doi:10.1016/j.foodchem.2012.04.125

CNU IR > Pharmacy and Science > Dept. of Cosmetic Science and institute of cosmetic science > Periodical Articles > Item 310902800/27527

Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/27527

Title:	Inhibitory effects of water extract from longan twigs on mutation and nitric oxide production
Authors:	Wang, Bor-Sen Tang, Chi-Hua Chiu, Chih-Kwang Huang, Ming-Hsing
Contributors:	化妝品應用與管理系生活應用與保健系食品科技系
Keywords:	Longan Twigs Mutation Nitric Oxide Tyrosinase
Date:	2012-11-15
Issue Date:	2014-03-21 16:12:27 (UTC+8)
Publisher:	Elsevier Sci Ltd
Abstract:	This study examines the inhibitory effects of water extract from longan twigs (WLTs) on mutation and nitric oxide (NO) production. The results show that WLT inhibited the mutagenicity of 2-aminoanthracene (2-AA), an indirect mutagen, and 4-nitroquinoline-N-oxide (4-NQO), a direct mutagen toward Salmonella typhimurium TA 98 and TA 100. In addition, WLT in the range 0-0.6 mg/ml showed radical scavenging, reducing activities and chelating activity, as well as decreased lipid oxidative damage. Meanwhile, WLT also inhibited tyrosinase activity and NO generation in lipopolysaccharide (LPS) stimulated macrophages. High performance liquid chromatography analysis suggests that the major phenolic constituents in WLT are epicatechin, ellagic acid and gallic acid. These bioactive components may contribute to the protective effects of WLT. Our data suggests that WLT can be applied to antimutation, anti-inflammation and antityrosinase. (C) 2012 Elsevier Ltd. All rights reserved.
Relation:	Food Chemistry, 135(2), 440-445
Appears in Collections:	[Dept. of Cosmetic Science and institute of cosmetic science] Periodical Articles [Dept. of Life and Health Science] Periodical Articles [Dept. of Food Science & Technology] Periodical Articles

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