Studies on The Antimicrobial Activities of Some Natural Coumarins

CNU IR > Chna Nan Annual Bulletin > Vol.7 (1981) > Item 310902800/27099

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Title:	Studies on The Antimicrobial Activities of Some Natural Coumarins 對於某些天然香豆素(Coumarin)之抗菌性的研討
Authors:	Yeh, Hsiao-yen Tian-shungWu
Contributors:	私立嘉南藥學專科學校
Date:	1981
Issue Date:	2013-11-12 13:50:16 (UTC+8)
Abstract:	The antimicrobial activities of 24 natural coumarins on the nine strains of bacterium and two strains of fungi have examined by using the agar-dilution-plate method, amoung them, only four coumarins, namely, demethylsuberosin, limettin, nordentatin and (-)-heraclenin, showed significant effects, and the most attractive fact was that nordentatin, with very low concentration level (10 ppm) still showed completely inhibitory effects against most of the bacterial strains being tested. 本報告以平碟稀釋法(Agar-dilution plate method)測定24種天然香豆素對九種細菌和二種黴菌之抗菌能力，發現其中的四種，即demethylsuberosin, limettin, nordentatin及(－)-heraclenin具有抗菌力。Demethylsuberosin在500ppm之濃度下對黴菌有完全之抑制力，而在100ppm之濃度時，則對大部份之細菌有抑制力Limettin在200ppm之濃度下對部份革蘭氏陰性細菌有效，(－)-Heraclenin在500ppm之濃度下，對E.coli病原性之pneumococlus及Pseudomonas aerugenosa有效。最令人注意的是Nordentatin，它在10ppm之濃度下，仍對大部份之實驗細菌有抗菌力。
Relation:	嘉南學報 7, (轉載論文) 台灣藥學雜誌第三十一卷第二期(1979)
Appears in Collections:	[Chna Nan Annual Bulletin] Vol.7 (1981)

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