Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/26710
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    Title: Antioxidant and antityrosinase activity of aqueous extracts of green asparagus
    Authors: Wang, Bor-Sen
    Chang, Lee-Wen
    Wu, Horng-Cherng
    Huang, Shu-Ling
    Chu, Heuy-Ling
    Huan, Ming-Hsing
    Contributors: 生活應用與保健系
    食品科技系
    化粧品應用與管理系
    Keywords: Green asparagus
    Melanin
    Tyrosinase
    Antioxidation
    Chromatography
    Date: 2011-07
    Issue Date: 2013-06-21 16:52:16 (UTC+8)
    Publisher: Elsevier
    Abstract: The effect of aqueous extracts of green asparagus (AGA) on antioxidation and tyrosinase inhibition in acellular and cellular systems was investigated. The results showed that AGA inhibited tyrosinase with an IC50 value of 1.21 mg/ml in a mixed-type inhibition. In the range of 0.05–1 mg/ml, the inhibitory effect on tyrosinase activity in B16 cells increased with increasing concentration of AGA. Meanwhile, the levels of glutathione in B16 cells were elevated by AGA in comparison to the control. In addition, AGA, in the range of 0.1–0.5 mg/ml, also exhibited radical scavenging, chelating activities and protected liposome against oxidative damage. The high performance liquid chromatography analysis indicated that polyphenolic components such as rutin, quercetin, kaempferol, and isorhamnetin were present in the AGA. This study suggested that AGA could play an important role in the regulation of tyrosinase activity and seem to be a natural inhibitor of browning reaction.
    Relation: Food Chemistry 127(1), pp. 141-146
    Appears in Collections:[Dept. of Recreation and Health-Care Management] Periodical Articles
    [Dept. of Food Science & Technology] Periodical Articles
    [Dept. of Cosmetic Science and institute of cosmetic science] Periodical Articles

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