Cardiovascular protection of deep-seawater drinking water in high-fat/cholesterol fed hamsters

doi:10.1016/j.foodchem.2011.01.116

CNU IR > College of Smart Living > Dept. of Life and Health Science > Periodical Articles > Item 310902800/26708

jsp.display-item.identifier=請使用永久網址來引用或連結此文件: https://ir.cnu.edu.tw/handle/310902800/26708

题名:	Cardiovascular protection of deep-seawater drinking water in high-fat/cholesterol fed hamsters
作者:	Hsu, Chin-Lin Chang, Yuan-Yen Chiu, Chih-Hsien Yang, Kuo-Tai Wang, Yu Fu, Shih-Guei Chen, Yi-Chen
贡献者:	生活應用與保健系
关键词:	Deep seawater Cardiovascular protection LDL receptor CYP7A1 Hamster Serum lipids Serum lipid peroxidation
日期:	2011-08
上传时间:	2013-06-20 15:53:06 (UTC+8)
出版者:	Elsevier
摘要:	Cardiovascular protection of deep-seawater (DSW) drinking water was assessed using high-fat/cholesterol-fed hamsters in this study. All hamsters were fed a high-fat/cholesterol diet (12% fat/0.2% cholesterol), and drinking solutions were normal distiled water (NDW, hardness: 2.48 ppm), DSW300 (hardness: 324.5 ppm), DSW900 (hardness: 858.5 ppm), and DSW1500 (hardness: 1569.0 ppm), respectively. After a 6-week feeding period, body weight, heart rates, and blood pressures of hamsters were not influenced by DSW drinking waters. Serum total cholesterol (TC), triacylglycerol (TAG), atherogenic index, and malondialdehyde (MDA) levels were decreased (p < 0.05) in the DSW-drinking-water groups, as compared to those in the NDW group. Additionally, increased (p < 0.05) serum Trolox equivalent antioxidant capacity (TEAC), and faecal TC, TAG, and bile acid outputs were measured in the DSW-drinking-water groups. Hepatic low-density-lipoprotein receptor (LDL receptor) and cholesterol-7α-hydroxylase (CYP7A1) gene expressions were upregulated (p < 0.05) by DSW drinking waters. These results demonstrate that DSW drinking water benefits the attenuation of high-fat/cholesterol-diet-induced cardiovascular disorders in hamsters.
關聯:	Food Chemistry 127(3), pp. 1146-1152
显示于类别:	[Dept. of Life and Health Science] Periodical Articles

文件中的档案:

档案	描述	大小	格式	浏览次数
index.html		0Kb	HTML	3241	检视/开启

在CNU IR中所有的数据项都受到原著作权保护.

TAIR相关文章

数据加载中.....