Inhibitory effects of molasses on mutation and nitric oxide production

doi:10.1128/AEM.01595-07

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標題:	Inhibitory effects of molasses on mutation and nitric oxide production
作者:	Wang, Bor-Sen Chang, Lee-Wen Kang, Zhi-Chyang Chu, Heuy-Ling Tai, Huo-Mu Huang, Ming-Hsing
貢獻者:	生活應用與保健系食品科技系保健營養系(所) 化粧品應用與管理系
關鍵字:	Molasses Mutation Nitric oxide Lipopolysaccharide Antioxidation
日期:	2011-06
上傳時間:	2013-06-20 15:52:57 (UTC+8)
出版者:	Elsevier Amer Soc Microbiology
摘要:	In this study, the effects of four molasses related products including cane molasses (CM), carob molasses (CAM), grape molasses (GM), and sorghum molasses (SM) on the antimutation and nitric oxide (NO) production were examined. The results showed that the four molasses products, particularly CAM, inhibited the mutagenicity of 2-aminoanthracene (2-AA), an indirect mutagen; and 4-nitroquinoline-N-oxide (4-NQO), a direct mutagen in Salmonellatyphimurium TA98 and TA100. In addition, CAM also showed a higher ABTS radical inhibition, reducing activity, and decreasing lipid oxidative damage more than the others kinds of molasses. In the range of 0–0.8 mg/ml, the inhibitory effect of all molasses products on NO generation in lipopolysaccharide (LPS) stimulated macrophages increased with increasing concentrations, and CAM showed the best inhibition of NO production. These data suggested that the four molasses related products display their biological activities in terms of antioxidation, antimutation, and anti-inflammation.
關聯:	Food Chemistry 126(3), pp. 1102-1107
顯示於類別:	[生活保健科技系] 期刊論文 [ 食品科技系 ] 期刊論文 [保健營養系(所) ] 期刊論文 [化妝品應用與管理系(所)] 期刊論文

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