Effects of the aqueous extract of sugarcane leaves on antimutation and nitric oxide generation

doi:10.1016/j.foodchem.2010.06.060

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標題:	Effects of the aqueous extract of sugarcane leaves on antimutation and nitric oxide generation
作者:	Wang, Bor-Sen Duh, Pin-Der Wu, She-Ching Huang, Ming-Hsing
貢獻者:	生活應用與保健系食品科技系化粧品應用與管理系
關鍵字:	Sugarcane leaves Mutation Nitric oxide Lipopolysaccharide Polyphenolics
日期:	2011-01
上傳時間:	2013-06-20 15:52:54 (UTC+8)
出版者:	Elsevier Elsevier Sci Ltd
摘要:	In this study, the effects of a water extract of sugarcane leaves (WSL) on antimutation and nitric oxide (NO) production were investigated. The results showed that WSL inhibited the mutagenicity of benzo[a]pyrene (BP), an indirect mutagen; and N-methyl-N′-nitrosoguanidine (MNNG), a direct mutagen toward Salmonella typhimurium TA 98 and TA 100. In addition, WSL, in the range of 0–0.4 mg/ml, showed superoxide inhibiting, NO scavenging, and reducing activity, as well as decreased lipid oxidative damage. In the range of 0–1 mg/ml, the inhibitory effect of WSL on NO generation in lipopolysaccharide (LPS) stimulated macrophages increased with increasing concentrations. A high performance liquid chromatography analysis revealed that the polyphenolic constituents, such as caffeic acid, ferulic acid, apigenin, and vitexin were present in WSL. These data suggested that WSL exhibiting biological activities could contribute to antimutation, anti-inflammation as well as antioxidation.
關聯:	Food Chemistry 124(2), pp. 495-500
顯示於類別:	[生活保健科技系] 期刊論文 [ 食品科技系 ] 期刊論文 [化妝品應用與管理系(所)] 期刊論文

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