含精油之乳液配方及其物化特徵

Chia Nan University of Pharmacy & Science Institutional Repository > 藥理學院 > 化妝品應用與管理系(所) > 博碩士論文 > Item 310902800/26106

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標題:	含精油之乳液配方及其物化特徵 The physicochemical characterization of emulsions containing an essential oil
作者:	吳奕賢
貢獻者:	化妝品科技研究所周宗翰梁家華
關鍵字:	乳液精油 emulsions essential oil
日期:	2012
上傳時間:	2012-11-27 11:35:11 (UTC+8)
摘要:	本研究擬開發以甜杏仁油(Sweet almond oil)及界面活性劑(Olivem 1000)為基礎之乳液配方，以包含薰衣草精油(Lavender oil)。藉由雷射粒徑分析儀、黏度計量測和微分掃描熱卡計，觀察不同配方之粒徑、黏度及相變行為等物化特性。當乳液配方中含3% Olivem 1000時，其平均粒徑大小會隨著甜杏仁油比例增加而變大，當乳液配方中Olivem 1000的含量為5%，其平均粒徑大小會隨著甜杏仁油含量比例增加而變小。在0.1 rpm轉速下，隨著甜杏仁油含量增加，黏度值明顯會變大。含3% Olivem 1000乳液的相變溫度為60℃，含5% Olivem 1000乳液的相變溫度為62℃，乳液中Olivem 1000比例增加，相變溫度略為提高，且熱焓量明顯增加，其中以3% Olivem 1000、5%薰衣草精油及30%甜杏仁油的乳液配方所需相變熱焓量最小。室溫下，乳液配方添加薰衣草精油5%具良好之物理穩定性。然而，在50℃下添加5%薰衣草精油後最多只能維持30天的穩定性。乳液配方之抑菌試驗中，5%薰衣草精油乳液有明顯延緩菌落數生長的功效。在精油之揮發對乳液重量變化試驗中，發現乳液配方可降低精油的揮發速率。乳液含30%甜杏仁油、3% Olivem 1000及5%薰衣草精油，為此研究發現最適化之配方。 The aim of this study is to develop a series of lotion formulas that use sweet almond oil natural lauryl polyglucose as bases and contain high concentration of lavender oil. The samples are measured by Laser Diffraction Submicron particle size analyzer and viscos meter and can be observed different size distribution diverseness of viscosity the variation of particle size and viscosity and their stability. When the rate of Olivem 1000 in the lotion formula is 3%, the average particle size will become bigger as the rate of sweet almond oil increase. On the other hand, if the rate of Olivem 1000 is 5%, the average particle size will become smaller when the rate of Sweet Almond oil increase. At the regular revolution (0.1 rpm), its viscosity will change obviously when the content of sweet almond oil increase. The transition temperature of lotion that contains 3% Olivem 1000 is at 60 degree and 5% Olivem 1000 is at 62 degree. Adding Olivem 1000 rate in the lotion, the transition temperature will rise a little and its enthalpy increase obviously. The lotion formula which contains 3% Olivem, 5% lavender essential oil and 30% sweet almond oil, the transition enthalpy it needs is the smallest. It can be found that lotion formulas adding 5% lavender essential oil have good physical stability at room temperature. However, they only can maintain at most 30 days stability after adding 5% essential oil at 50℃. From the antibacterial experiment on lotion formulas, we find out the efficacy of 5% lavender essential oil. That is it can postpone the growth of colonies. In addition, from the test of essential oils evaporation for the variation of lotion weight, it reveals lotion formulas can reduce essential oils evaporation rate. Therefore, the study was found 30% sweet almond oil, 3% Olivem 1000, and 5% lavender oil is the best formula.
關聯:	校內校外均不公開，學年度：100，65頁
显示于类别:	[化妝品應用與管理系(所)] 博碩士論文

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