| Title: | Electrosynthesis of fluorinated indole derivatives |
| Authors: | Bin Yin
Laihao Wang
Shinsuke Inagi
Toshio Fuchigami |
| Contributors: | 醫藥化學系 |
| Keywords: | Electrolytic fluorination
Fluoroindole derivatives
Fluoroindoline |
| Date: | 2010-08 |
| Issue Date: | 2012-06-04 15:45:09 (UTC+8) |
| Publisher: | Rgamon-Elsevier Science Ltd |
| Abstract: | Anodic fluorination of various N-acetyl-3-substituted indole derivatives was successfully carried out in Et4NF-4HF/MeCN to provide the corresponding trans-2,3-difluoro-2,3-dihydroindoles exclusively or selectively. Treatment of difluorinated products with a base provided monofluoroindole derivatives or monofluoroindoline derivative depending on the substituents at the 3-position. |
| Relation: | Tetrahedron 66(34)：p.6820-6825 |
| Appears in Collections: | [食藥產業暨檢測科技系(含五專)] 期刊論文
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