Electrosynthesis of fluorinated indole derivatives

CNU IR > Pharmacy and Science > Dept. of Food & Drug Industry and Inspective Technology > Periodical Articles > Item 310902800/25379

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Title:	Electrosynthesis of fluorinated indole derivatives
Authors:	Bin Yin Laihao Wang Shinsuke Inagi Toshio Fuchigami
Contributors:	醫藥化學系
Keywords:	Electrolytic fluorination Fluoroindole derivatives Fluoroindoline
Date:	2010-08
Issue Date:	2012-06-04 15:45:09 (UTC+8)
Publisher:	Rgamon-Elsevier Science Ltd
Abstract:	Anodic fluorination of various N-acetyl-3-substituted indole derivatives was successfully carried out in Et4NF-4HF/MeCN to provide the corresponding trans-2,3-difluoro-2,3-dihydroindoles exclusively or selectively. Treatment of difluorinated products with a base provided monofluoroindole derivatives or monofluoroindoline derivative depending on the substituents at the 3-position.
Relation:	Tetrahedron 66(34)：p.6820-6825
Appears in Collections:	[Dept. of Food & Drug Industry and Inspective Technology] Periodical Articles

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