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    Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/25253

    標題: Pyogenic Liver Abscess-comparison between Diabetic Patients and Non-diabetic Patients
    作者: Ming-Jeng Kuo
    Lein-Ray Mo
    Chien-Lin Chou
    Kuo-Kwan Chang
    Chun-Hsiang Wang
    Ruey-Chang Lin
    Jen-Juan Kuo
    Keh-Cherng Wey
    貢獻者: 餐旅管理系
    關鍵字: pyogenic liver abscess
    日期: 2010-12
    上傳時間: 2012-05-23 15:46:50 (UTC+8)
    摘要: Background and Aims: Pyogenic liver abscess (PLA) is a rare and life threatening disease. Diabetes is also known as the most common risk factor for PLA. The objective of this study is to compare the nature of PLA between patients with diabetes and without. We also tried to identify if diabetes was an independent predictor for mortality in patients with PLA.
    Methods: We conducted a retrospective study of 120 patients who presented with PLA from January 2003 to May 2009. Patients were divided into two groups depending on whether they had diabetes or not. Characteristics of these patients were analyzed by two-sample test for interval and categorical data. Significant predictors of mortality in patients with PLA were investigated by multivariate logistic regression.
    Results: Fifty percent of the 120 studied PLA patients were found with diabetes mellitus. Those PLA patients with diabetes were more likely to have a culture result of Klebsiella pneumonia and hypertension. In contrast, more PLA patients without diabetes had concomitant biliary stones, a history of hepatobiliary procedures, and elevated alkaline phosphatase level. These patients also received more treatment of catheter drainage. Diabetes was not an independent predictor for mortality in PLA. Impaired renal function with creatinine>1.5 g/dl (adjusted OR 5.4, 95% CI 1.4-20.8) and hypoalbuminemia with albumin<3.0 g/dl (adjusted OR 11.6, 95% CI 1.4-98.3) were independent predictors for mortality in PLA.
    Conclusion: There were several different characteristics between diabetic and non-diabetic PLA. Initial presentations with renal insufficiency and hypoalbuminemia were associated with poor prognosis in patients with PLA.
    結果:在120位的化膿性肝膿瘍患者中,有糖尿病的患者占了60位。分析比較兩組的結果發現,糖尿病的化膿性肝膿瘍患者有較高比例的細菌培養結果爲K pneumonia (P=0.003)及合併有高血壓(P=0.0007);非糖尿病的化膿性肝膿瘍患者有較高的比例合併膽道結石(P=0.036)、過去接受肝或膽道醫療處置的病史(P=0.049)、偏高的鹼性磷酸酶(P=0.034)以及較多患者接受膿瘍引流(P=0.05)。糖尿病並非是化膿性肝膿瘍患者死亡的預測因子。血清肌肝酸大於1.5 g/dl (adjusted OR 5.4, 95% CI 1.4-20.8)及血清白蛋白小於3.0 g/dl(adjusted OR 11.6, 95% CI 1.4-98.3)是造成化膿性肝膿瘍患者死亡的獨立預測因子。
    關聯: Gastroenterol Journal Taiwan 27(4):p.403-409
    Appears in Collections:[餐旅管理系] 期刊論文

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