In this study, we attempted to evaluate the effect on dispelling mental fatigue for eye massagers by using physiological indices including electroencephalography (EEG) and heart rate variability (HRV). Thirty university male students divided into experimental and control groups with 20 and 10 subjects respectively participated as volunteer subjects. They are paid for their participation in the study. Participants could lead to mental fatigue during 2 hours of experimental tasks (mental arithmetic via computer). After experimental tasks, their EEG and HRV were measured immediately. The participants of experiment group wore the eye massager for 15 minutes, while the ones of control group took a rest for 15 minutes with eyes closed only. We found EEG basic indices of and bands were decreased while band was increased for experiment group, and the degree was superior to the control group. In addition to basic indices, EEG ratio indices of (+)/ and / were decreased at the same condition, while/ was increased for experiment group, and the degree was also superior to the control group. It revealed that the alertness level of participant wearing the wye massager invreased more than that of one with eyes closed only. For measurement of HRV, the low frequency component (LF) of HRV arose and high frequency component (HF) reduced. The value of LF/HF ratio, i.e. sympathetic/parasympathetic balance index for experiment group decreased significantly more than that for control group. As mentioned above, the participants wearing the eye massager had significant relaxation and advantaged dispelling mental farigue. For subjective measure, the NASA-TLX rating scale of the experiment group had more mental relaxation than that of control group. The final results appeared that the eye massager had pronounced effect on dispelling mental fatigue and psychological relaxation.