A Novel Synthesis of Substituted Naphthalene

CNU IR > Pharmacy and Science > 2011 Taiwanese-Russian Organic, Medicinal and Bio Chemistry Interactions & PST Medicinal Chemistry Symposium > Item 310902800/24261

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Title:	A Novel Synthesis of Substituted Naphthalene
Authors:	Wei-Yu Chang (張偉昱) Yu-Chia Wen (文郁嘉) Ta-Hsien Chuang (莊大賢)
Date:	2011
Issue Date:	2011-06-23 14:57:44 (UTC+8)
Abstract:	Naphthalenes have been an interesting structural class of compounds by pharmacologists for many years, which have found many uses in the field of pharmaceuticals. Due to its wide applications in the field of pharmaceuticals, this group of compounds has attracted our attention. Recently, we developed an elticient method to synthesize highly substituted naphthalenes. A series of 2-phenyl naphthalenes, bearing electron-donating and electron-withdrawing substituents, were synthesized from 4,5-diphenyl-penta-2,4-dienoyl azides via the iodine-catalyzed thermal cyclization. The detailed mechanism was also discussed.
Relation:	2011年台俄有機、藥物與生物化學交流暨藥物化學研討會，起迄日：2011/04/06~2011/04/05，地點：溪頭台大實驗林
Appears in Collections:	[Pharmacy and Science] 2011 Taiwanese-Russian Organic, Medicinal and Bio Chemistry Interactions & PST Medicinal Chemistry Symposium

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