Novel Sesquiterpenoid from Pachira aquatica

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標題:	Novel Sesquiterpenoid from Pachira aquatica
作者:	Lin-Yang Cheng (鄭霖陽) Chin-Yen Chen (陳晉彦) Chang-Hui Liao (廖長輝) Mei-Ing Chung (鍾美英) Jih-Jung Chen (陳日榮)
日期:	2011
上傳時間:	2011-06-23 14:57:34 (UTC+8)
摘要:	Pachira aquatica Aublet (Bombacaceae) is an evergreen tree, distributed throughout tropical America, being widely cultivated in Asiatic countries, introduced tomainly in China, Japan and Taiwan. Cadinane type sesquiterpenoids, sesquiterpene lactones, and triterpenes are widely distributed in plants of the family Bombacaceae. Many of these compounds exhibit antiangiogenic, hypotensive, and antimicrobial activities. Investigation of rc-hexane-soluble fraction of the stem of R aquatica has led to the isolation of a new cadinane type sesquiterpene, pachiraquiatin A (1), together with ten known compounds, including seven flavonoids, 5-hydroxyaurnetin (2), kaempferol 3,7,4'-trimethyl ether (3), santin 7-methyl ether 3,5,6,7,8,3', 4'-heptamethoxyflavone (5), calycopterin (6), retusin (7), and -dihydroxy-3,7-dimethoxyflavone (8), two cadalene type sesquiter- penes, isohemigossylic acid lactone 7-methyl ether (9) and hibiscolactone A (10), and a triterpenoid, lupenone (11). The structures of the above isolates were determined through spectroscopic and MS analyses. This symposium describes the structural elucidation of 1 and the biological activities of the isolates.
關聯:	2011年台俄有機、藥物與生物化學交流暨藥物化學研討會，起迄日：2011/04/06~2011/04/05，地點：溪頭台大實驗林
显示于类别:	[藥理學院] 2011年台俄有機、藥物與生物化學交流暨藥物化學研討會

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