New Coumarin from the Fruits of Cnidium monnieri

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Title:	New Coumarin from the Fruits of Cnidium monnieri
Authors:	Yuan-Chih Chen (陳源智) Wei-Ting Gao (高威廷) Jih-Jung Chen (陳日榮)
Date:	2011
Issue Date:	2011-06-23 14:57:32 (UTC+8)
Abstract:	Cnidium monnieri (L.) Cusson (Umbelliferae) is a crude drug "Fructus Cnidii" (Chinese name Shechaungzi) used in traditional Chinese to treat impotence, frigidity, and skin-related disease. Coumarins, chromones, and their derivatives were isolated from this plant in previous studies. Many of these compounds were found to exhibit insecticidal, antiallergic, antifungal, and antibacterial activities. Investigation on EtOAc-soluble fraction of the fruits of C. monnieri has led to the isolation of a new coumarin, cnidimonnin (1), together with 7 known coumarins, including meranzin hydrate (2), peroxyauraptenol (3), auraptenol (4), bergapten (5), isopimpinellin (6), osthol (7), and xanthotoxin (8). The structure of new compound 1 was determined through spectroscopic and MS analyses. This symposium describes the structural elucidation of 1 and the biological activities of the isolates.
Relation:	2011年台俄有機、藥物與生物化學交流暨藥物化學研討會，起迄日：2011/04/06~2011/04/05，地點：溪頭台大實驗林
Appears in Collections:	[Pharmacy and Science] 2011 Taiwanese-Russian Organic, Medicinal and Bio Chemistry Interactions & PST Medicinal Chemistry Symposium

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