Synthetic Development and Mechanistic Study on Pd(II)-Catalyzed Cyclization of Enediynes to Benzo[a]carbaxoles

jsp.display-item.identifier=請使用永久網址來引用或連結此文件: https://ir.cnu.edu.tw/handle/310902800/24198

標題:	Synthetic Development and Mechanistic Study on Pd(II)-Catalyzed Cyclization of Enediynes to Benzo[a]carbaxoles
作者:	Chin-Chau Chen (陳景昭) Lin-Yu Chin (金玲宇) Shyh-Chyun Yang (楊世群) Ming-Jung Wu (吳明忠)
日期:	2011
上傳時間:	2011-06-23 14:56:54 (UTC+8)
摘要:	Treatment of N,N-dimethyl 2-[2-(2-ethynylphenyl)ethynyl] anilines (1) with 10 mol % of palladium chloride and 2 equiv of cupric chloride in n refluxing THF gave benzo[a]carbazoles (2) in good yields. A mechanistic study showed that this reaction must proceed through formation of haloindole (3) followed by a palladium(II)-catalyzed atom transfer cyclization reaction to give the benzo[a]carbazoles.
關聯:	2011年台俄有機、藥物與生物化學交流暨藥物化學研討會，起迄日：2011/04/06~2011/04/05，地點：溪頭台大實驗林
显示于类别:	[藥理學院] 2011年台俄有機、藥物與生物化學交流暨藥物化學研討會

文件中的档案:

档案	描述	大小	格式	浏览次数
op-10.pdf		58Kb	Adobe PDF	505	检视/开启

在CNU IR中所有的数据项都受到原著作权保护.

TAIR相关文章