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    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/22569

    標題: 以高效液相層析儀定量化妝品中水楊酸成分
    Determination of Salicylic Acid in Cosmetic Formulation by High Performance Liquid Chromatography
    作者: 張妙玲
    貢獻者: 化妝品應用管理系
    關鍵字: 化妝品配方
    cosmetic formulations
    salicylic acid
    日期: 1999
    上傳時間: 2010-04-08 13:44:27 (UTC+8)
    摘要: 本研究主要目的在於開發─簡單快速的逆相HPLC分析方法以測定化妝品中水楊酸的含量。以甲醇\水(含0.05M磷酸)=85\15為移動相進行單一分離(isocraticseparation)可得到最佳分離效果,分析所用的分離管柱是Mightysil RP-18 GP(5μm,20×4.6mm i.d.)、流速為1.1mL/min並以254nm為偵測波長。其線性範圍為5g/mL至100g/mL,相關係數(correlation coefficient)=0.998,變異係數值(CV)為1.15%,回收率達99%。
    A simple, rapid and reliable high performance liquid chromatographic method for determinatin of salicylic acid (SA) in cosmetic formulations has been developed. Isocratic separation was performed using an Mightysil RP-18GP column ( 5μm, 25cm x 4.6mm i.d.) with a mobile phase MeOH: H20 in 0.05M H3PO4 (75: 25, v/v). flow rate 1.1 mL/min and UV detector at 254 nm. The peak high response versus concentration was coefficients were O.998, and the coefficient of variation and the recovery were respectively, 1.15% and 99%.
    關聯: 嘉南學報 25 : p.201-208
    Appears in Collections:[嘉南學報] 25 期 (1999)
    [化妝品應用與管理系(所)] 期刊論文
    [醫藥化學系 ] 期刊論文

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