Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/22185
English  |  正體中文  |  简体中文  |  Items with full text/Total items : 18272/20499 (89%)
Visitors : 16417198      Online Users : 1956
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: https://ir.cnu.edu.tw/handle/310902800/22185


    题名: Microwave-assisted acid hydrolysis of toluene diamine conjugates in urine samples for biomarkers in toluene diisocyanate analysis
    作者: Hui-Jung Yeh
    Wei-Chao Lin
    Shiann-Cherng Sheu
    Tung-Sheng Shih
    Lien-Huei Chen
    Ho-Yuan Chang
    贡献者: 嬰幼兒保育系
    关键词: Toluene diisocyanate
    Toluene diamine
    Microwave-assisted heating
    Hydrolysis
    日期: 2007-06
    上传时间: 2010-01-11 14:08:07 (UTC+8)
    摘要: Toluene diamines (TDAs) in urine have been used widely to determine the amount of toluene diisocyanate (TDI) absorbed by humans. Conventional hydrolysis to prepare a sample of urine takes approximately 16 h. An attempt is made to apply microwave-assisted heating (MAH) to reduce the duration of analysis. Urine collected from rats exposed to a mixture of 2,4- and 2,6-TDI was diluted with non-exposed human urine 1/1250-, 1/500- and 1/250-fold. The urine samples were hydrolyzed by both conventional heating and MAH. The hydrolysis efficiency obtained using MAH significantly exceeded that obtained using conventional heating. Hydrolysis by MAH required only 20 min, 48 times faster than with conventional heating. The use of the MAH method in hydrolysis was demonstrated to be reproducible, timesaving and efficient technique in measuring the concentration of urinary TDAs.
    關聯: Talanta 72(6) : p.1527-1532
    显示于类别:[Dept. of Childhood Education and Nursery] Periodical Articles

    文件中的档案:

    档案 大小格式浏览次数
    0KbUnknown3210检视/开启


    在CNU IR中所有的数据项都受到原著作权保护.

    TAIR相关文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈