Diversity of polyketide synthases found in the Aspergillus and Streptomyces genomes

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Title:	Diversity of polyketide synthases found in the Aspergillus and Streptomyces genomes
Authors:	James F. Sanchez Yi-Ming Chiang Clay C. C. Wang
Contributors:	藥物科技研究所
Keywords:	Fungal natural product Aspergillus polyketide synthase polyketides secondary metabolite
Date:	2008-03
Issue Date:	2009-10-13 09:29:35 (UTC+8)
Publisher:	Amer Chemical Soc
Abstract:	Natural products produced by biological organisms have played an important role in human health. The genomes of several Aspergillus species and several Streptomyces species have recently been sequenced. Interestingly the genomes revealed a large range of secondary metabolite genes, for many of which the products are currently unknown, suggesting that there is a wealth of secondary metabolites yet to be discovered. This brief review will discuss the current knowledge in polyketides produced by the various different classes of polyketide synthases (PKSs) present in the Aspergillus and Streptomyces genomes.
Relation:	Molecular Pharmaceutics 5(2)：p.226-233
Appears in Collections:	[Dept. of Pharmacy] Periodical Articles

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