New Benzoyl Glucosides and Cytotoxic Pterosin Sesquiterpenes from Pteris ensiformis Burm

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Title:	New Benzoyl Glucosides and Cytotoxic Pterosin Sesquiterpenes from Pteris ensiformis Burm
Authors:	Yung-Husan Chen Fang-Rong Chang Mei-Chin Lu Pei-Wen Hsieh Ming-Jiuan Wu Ying-Chi Du Yang-Chang Wu 吳明娟
Contributors:	生物科技系
Keywords:	Pteris ensiformis pterosin B human leukemia
Date:	2008-02
Issue Date:	2009-07-21 14:06:56 (UTC+8)
Publisher:	Molecular Diversity Preservation Int
Abstract:	Three new compounds: 2R,3R-pterosin L 3-O-β-D-glucopyranoside (1), β-Dxylopyranosyl(1→2)-7-O-benzoyl-β-D- lucopyranoside (2) and 4-O-benzoyl-β-D-xylopyranosyl(1→2)-7-O-benzoyl-β-D-glucopyranoside (3), together with nine known compounds, were isolated from the ethyl acetate extract of Pteris ensiformis. 5-[2-Hydroxyethylidene]-2(5H)-uranone (4), which had been synthesized, was isolated from natural sources for the first time. The structures of all isolated compounds were determined on the basis of mass and spectroscopic evidence. Compound 1 and pterosin B (5) show cytotoxicity against HL 60 cells (human leukemia) with the IC50 values of 3.7 and 8.7 μg/mL, respectively.
Relation:	Molecules 13(2)：p.255-266
Appears in Collections:	[Dept. of Biotechnology (including master's program)] Periodical Articles

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