控制釋放技術是利用高分子材料將物質以包覆,吸收,鍵結的方式 ,使物質在輸送過程中減少或不受破壞,於目的地後緩慢釋放以避免過量或不足, 實驗擬利用微小球以高分子化合物將物質包覆於300-500微米之粒子作為控制釋放之材料
研究主要探討製備甲基丙烯酸甲酯系微小球所需條件,包括共單體的種類,比例,分別探討不同條件下所形成之微小球控制釋放之效果 The polymeric microencapsulation is normally used for the controlled release delivery
of microencapsulated drugs and for targeting drug delivery. It can also be utilized in major
industrial fields and environmental on a specific site. The drug substances presently available
for use in clinical medicine are often highly active pharmacological substances. In many cases,
drug molecules have specific site of action, either in certain tissues of the body or on certain
receptor sites.
The performance of controlled delivery device is on the polymeric microencapsulation .
So our goal is concerned with the amount of the drug release of Mrthyl methacrylate microencapsulation. The effects of various preparation parameters, monomer and comonomer species and particles size , on the drug controlled release will be extensively studied .