Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/1108
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    標題: 化妝品塑身燃脂霜中氨茶鹼經皮吸收代謝之研究
    作者: 王來好
    貢獻者: 醫藥化學系
    關鍵字: 經皮吸收
    氨茶鹼促進劑
    傅立葉轉換紅外線
    減弱全反射
    Percutaneous absorption
    aminophylline
    enhancers
    FT-IR
    ATR
    日期: 2003
    上傳時間: 2008-06-26 13:39:37 (UTC+8)
    出版者: 台南縣:嘉南藥理科技大學醫藥化學系
    摘要: 研究含皮膚促進劑之各種基劑與皮膚接觸後,以ATR (attenated total reflection) 傅立葉轉換紅外線光譜儀 (FTIR)測定氨茶鹼在皮膚之傳送。由於存在光譜帶的N-H鍵頻率特性,可提供氨茶鹼在皮膚的吸收。研究三種皮膚促進劑(植物油、精油及親油性物質),以親油性物質 β- cyclodextrin對氨茶鹼促進吸收最大。
    The delivery of aminophylline from several vehicles, including those containing penetration enhancers, was investigated in human skin. The skin after contact with the aminophylline formulation was examined by attenated total reflection (ATR) - Fourier transform infrared (FTIR) spectroscopy. The presence of spectral bands at frequencies characteristic of N-H bonds provides evidence for the adsorption of the aminophylline on skin. Of the three kinds penetration enhancers ( plant oils, essentials oils and lipophilicities) were studied, β- cyclodextrin exhibited the largest increase intransdemal delivery when various enhancers were used .
    關聯: 計畫編號:CNAC9206
    显示于类别:[醫藥化學系 ] 校內計畫

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